MYC and KRAS cooperation: from historical challenges to therapeutic opportunities in cancer
S Casacuberta-Serra, Í González-Larreategui… - … and Targeted Therapy, 2024 - nature.com
RAS and MYC rank amongst the most commonly altered oncogenes in cancer, with RAS
being the most frequently mutated and MYC the most amplified. The cooperative interplay …
being the most frequently mutated and MYC the most amplified. The cooperative interplay …
Multi-omics analyses based on genes associated with oxidative stress and phospholipid metabolism revealed the intrinsic molecular characteristics of pancreatic …
H Wang, H Guo, J Sun, Y Wang - Scientific Reports, 2023 - nature.com
Oxidative stress (OS), which impacts lipid metabolic reprogramming, can affect the biological
activities of cancer cells. How oxidative stress and phospholipid metabolism (OSPM) …
activities of cancer cells. How oxidative stress and phospholipid metabolism (OSPM) …
Hairpin-Empowered Invasive Reaction Combined with Catalytic Hairpin Assembly Cascade Amplification for the Specific Detection of Single-Nucleotide …
Y Zhang, S Xu, M Luo, J Chen, L Wang… - Analytical …, 2024 - ACS Publications
Single-nucleotide polymorphism (SNP) is widely used in the study of disease-related genes
and in the genetic study of animal and plant strains. Therefore, SNP detection is crucial for …
and in the genetic study of animal and plant strains. Therefore, SNP detection is crucial for …
Identification of a 9-gene signature to enhance biochemical recurrence prediction in primary prostate cancer: A benchmarking study using ten machine learning …
Prostate cancer (PCa) is a prevalent malignancy among men worldwide, and biochemical
recurrence (BCR) after radical prostatectomy (RP) is a critical turning point commonly used …
recurrence (BCR) after radical prostatectomy (RP) is a critical turning point commonly used …
Mammalian START-like phosphatidylinositol transfer proteins–Physiological perspectives and roles in cancer biology
A Pathak, KG Willis, VA Bankaitis… - Biochimica et Biophysica …, 2024 - Elsevier
PtdIns and its phosphorylated derivatives, the phosphoinositides, are the biochemical
components of a major pathway of intracellular signaling in all eukaryotic cells. These lipids …
components of a major pathway of intracellular signaling in all eukaryotic cells. These lipids …
An enzyme-free fluorescence sensing platform based on multiplex toehold-mediated strand displacement for point-of-care testing of single nucleotide polymorphisms
Y Zhang, Y Chen, M Luo, L Wang, J Chen… - Sensors and Actuators B …, 2024 - Elsevier
Single nucleotide polymorphisms (SNPs) are biomarkers for the prediction and diagnosis of
biomedical diseases, as well as important reference markers for intelligent design and …
biomedical diseases, as well as important reference markers for intelligent design and …
[PDF][PDF] PITPNC1 调控肿瘤细胞脂质代谢与铁死亡的研究进展
张皓翔， 张赛 - 中国普通外科杂志, 2024 - zpwz.net
摘要脂质代谢介导铁死亡在肿瘤发生发展过程中起至关重要的作用, 已成为当前肿瘤研究领域
热点和难点. 目前肿瘤相关调控脂质代谢和铁死亡的关键调节分子仍然不是十分清楚. 研究表明 …
热点和难点. 目前肿瘤相关调控脂质代谢和铁死亡的关键调节分子仍然不是十分清楚. 研究表明 …
The Role of PITPNC1 in Lung Adenocarcinoma: Differential Expression, Immune Infiltration, and Prognostic Significance
C Li, J Chen, G Zhang, F Guo, X Zhang - medRxiv, 2024 - medrxiv.org
Lung adenocarcinoma (LUAD) is one of the most prevalent and deadly forms of lung cancer,
necessitating the identification of novel biomarkers for diagnosis and prognosis. This study …
necessitating the identification of novel biomarkers for diagnosis and prognosis. This study …