Desert endemic plants in Algeria: A review on traditional uses, phytochemistry, polyphenolic compounds and pharmacological activities
Due to their robust antioxidant capabilities, potential health benefits, wide variety of
biological activities, and strong antioxidant qualities, phenolic compounds are substances …
biological activities, and strong antioxidant qualities, phenolic compounds are substances …
Synthesis and biological evaluation of organoselenium (NSAIDs-SeCN and SeCF3) derivatives as potential anticancer agents
X He, M Zhong, S Li, X Li, Y Li, Z Li, Y Gao… - European Journal of …, 2020 - Elsevier
A series of organoselenium compounds based on the hybridization of nonsteroidal
antiinflammatory drugs (NSAIDs) scaffolds and Se functionalities (-SeCN and-SeCF 3) were …
antiinflammatory drugs (NSAIDs) scaffolds and Se functionalities (-SeCN and-SeCF 3) were …
Synthesis and biochemical studies of novel organic selenides with increased selectivity for hepatocellular carcinoma and breast adenocarcinoma
S Shaaban, AM Ashmawy, A Negm… - European Journal of …, 2019 - Elsevier
Nineteen organoselenides were synthesized and tested for their intrinsic cytotoxicity in
hepatocellular carcinoma (HepG2) and breast adenocarcinoma (MCF-7) cell lines and their …
hepatocellular carcinoma (HepG2) and breast adenocarcinoma (MCF-7) cell lines and their …
New organoselenides (NSAIDs-Se derivatives) as potential anticancer agents: Synthesis, biological evaluation and in silico calculations
X He, Y Nie, M Zhong, S Li, X Li, Y Guo, Z Liu… - European Journal of …, 2021 - Elsevier
Herein we reported the synthesis of twenty new organoselenium compounds (2a-2j and 3a-
3j) based on the hybridization of nonsteroidal antiinflammatory drugs (NSAIDs) skeleton and …
3j) based on the hybridization of nonsteroidal antiinflammatory drugs (NSAIDs) skeleton and …
The genus Genista L.: A rich source of bioactive flavonoids
The genus Genista L.(family Fabaceae, subfamily Papilionoideae), with its cosmopolitan
distribution, has attracted the human interest since ancient times, as it is used in folk …
distribution, has attracted the human interest since ancient times, as it is used in folk …
Combinatorial synthesis, in silico, molecular and biochemical studies of tetrazole-derived organic selenides with increased selectivity against hepatocellular …
S Shaaban, A Negm, AM Ashmawy, DM Ahmed… - European Journal of …, 2016 - Elsevier
Novel tetrazole-based diselenides and selenoquinones were synthesized via azido-Ugi and
sequential nucleophilic substitution (SN) strategy. Molecular docking study into mammalian …
sequential nucleophilic substitution (SN) strategy. Molecular docking study into mammalian …
Organoselenocyanates and symmetrical diselenides redox modulators: Design, synthesis and biological evaluation
Oxidative stress (OS) and disturbed intracellular redox balance have been predominantly
observed in different types of cancer, including hepatocellular carcinoma (HCC). Agents …
observed in different types of cancer, including hepatocellular carcinoma (HCC). Agents …
[HTML][HTML] Cytoprotective organoselenium compounds for oligodendrocytes
S Shaaban, A Zarrouk, D Vervandier-Fasseur… - Arabian Journal of …, 2021 - Elsevier
Herein we report the synthesis of peptide-like and tetrazole-based organoselenium
compounds via Ugi and Ugi-azide reactions, respectively. The organoselenium compounds' …
compounds via Ugi and Ugi-azide reactions, respectively. The organoselenium compounds' …
Anticancer activity, dual prooxidant/antioxidant effect and apoptosis induction profile of new bichalcophene-5-carboxamidines
A series of thirteen new aryl/hetarylbichalcophene-5-carboxamidines was prepared and
screened for an in vitro anti-proliferative activity against sixty cancer cell lines. The tested …
screened for an in vitro anti-proliferative activity against sixty cancer cell lines. The tested …
Expeditious entry to functionalized pseudo-peptidic organoselenide redox modulators via sequential Ugi/SN methodology
S Shaaban, A Negm, M A. Sobh… - Anti-Cancer Agents in …, 2016 - benthamdirect.com
An efficient route towards the synthesis of symmetrical diselenide and seleniumcontaining
quinone pseudopeptides via one-pot Ugi and sequential nucleophilic substitution (SN) …
quinone pseudopeptides via one-pot Ugi and sequential nucleophilic substitution (SN) …