Endothelial fluid shear stress sensing in vascular health and disease

N Baeyens, C Bandyopadhyay… - The Journal of …, 2016 - Am Soc Clin Investig
Endothelial cells transduce the frictional force from blood flow (fluid shear stress) into
biochemical signals that regulate gene expression and cell behavior via specialized …

CD36: implications in cardiovascular disease

M Febbraio, RL Silverstein - The international journal of biochemistry & cell …, 2007 - Elsevier
CD36 is a broadly expressed membrane glycoprotein that acts as a facilitator of fatty acid
uptake, a signaling molecule, and a receptor for a wide range of ligands, including apoptotic …

Au‐Doped Ag2Te Quantum Dots with Bright NIR‐IIb Fluorescence for In Situ Monitoring of Angiogenesis and Arteriogenesis in a Hindlimb Ischemic Model

H Yang, H Huang, X Ma, Y Zhang, X Yang… - Advanced …, 2021 - Wiley Online Library
Abstract Fluorescence located in 1500–1700 nm (denoted as the near‐infrared IIb window,
NIR‐IIb) has drawn great interest for bioimaging, owing to its ultrahigh tissue penetration …

A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells

BG Coon, S Timalsina, M Astone, ZW Zhuang… - Journal of Cell …, 2022 - rupress.org
Atherosclerosis, the major cause of myocardial infarction and stroke, results from converging
inflammatory, metabolic, and biomechanical factors. Arterial lesions form at sites of low and …

Near‐infrared IIb fluorescence imaging of vascular regeneration with dynamic tissue perfusion measurement and high spatial resolution

Z Ma, M Zhang, J Yue, C Alcazar… - Advanced functional …, 2018 - Wiley Online Library
Real‐time optical imaging is a promising approach for visualizing in vivo hemodynamics
and vascular structure in mice with experimentally induced peripheral arterial disease …

VEGF‐B‐induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart

R Kivelä, M Bry, MR Robciuc, M Räsänen… - EMBO molecular …, 2014 - embopress.org
Angiogenic growth factors have recently been linked to tissue metabolism. We have used
genetic gain‐and loss‐of function models to elucidate the effects and mechanisms of action …

Molecular controls of arterial morphogenesis

M Simons, A Eichmann - Circulation research, 2015 - Am Heart Assoc
Formation of arterial vasculature, here termed arteriogenesis, is a central process in
embryonic vascular development as well as in adult tissues. Although the process of …

Biomechanical factors as triggers of vascular growth

IE Hoefer, B den Adel… - Cardiovascular research, 2013 - academic.oup.com
Haemodynamic factors influence all forms of vascular growth (vasculogenesis,
angiogenesis, arteriogenesis). Because of its prominent role in atherosclerosis, shear stress …

State-of-the-art methods for evaluation of angiogenesis and tissue vascularization: a scientific statement from the American Heart Association

M Simons, K Alitalo, BH Annex, HG Augustin… - Circulation …, 2015 - Am Heart Assoc
The American Heart Association makes every effort to avoid any actual or potential conflicts
of interest that may arise as a result of an outside relationship or a personal, professional, or …

Porcine host defense peptides: expanding repertoire and functions

Y Sang, F Blecha - Developmental & Comparative Immunology, 2009 - Elsevier
Host defense peptides (HDPs) are a large group of innate immune effectors that are also
termed antimicrobial peptides. Because of the rapid progress that has been made in …