Ca2+ homeostasis and endoplasmic reticulum (ER) stress: An integrated view of calcium signaling
J Krebs, LB Agellon, M Michalak - Biochemical and biophysical research …, 2015 - Elsevier
Cellular Ca 2+ homeostasis is maintained through the integrated and coordinated function
of Ca 2+ transport molecules, Ca 2+ buffers and sensors. These molecules are associated …
of Ca 2+ transport molecules, Ca 2+ buffers and sensors. These molecules are associated …
Inositol Trisphosphate Receptor Ca2+ Release Channels
The inositol 1, 4, 5-trisphosphate (InsP3) receptors (InsP3Rs) are a family of Ca2+ release
channels localized predominately in the endoplasmic reticulum of all cell types. They …
channels localized predominately in the endoplasmic reticulum of all cell types. They …
Bell-shaped calcium-response curves of lns(l,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum
llya Bezprozvanny, J Watras, BE Ehrlich - Nature, 1991 - nature.com
RELEASE of calcium from intracellular stores occurs by two pathways, an inositol 1, 4, 5-
trisphosphate (InsP3)-gated channel1–3 and a calcium-gated channel (ryanodine receptor) …
trisphosphate (InsP3)-gated channel1–3 and a calcium-gated channel (ryanodine receptor) …
2APB, 2-Aminoethoxydiphenyl Borate, a Membrane-Penetrable Modulator of Ins(1,4,5)P3-Induced Ca2+ Release
T Maruyama, T Kanaji, S Nakade… - The journal of …, 1997 - academic.oup.com
The effects of a novel membrane-penetrable modulator, 2APB (2-aminoethoxy diphenyl
borate), on Ins (1, 4, 5) P3-induced Ca2+ release were examined. 2APB inhibited Ins (1, 4 …
borate), on Ins (1, 4, 5) P3-induced Ca2+ release were examined. 2APB inhibited Ins (1, 4 …
Cerebellar long-term depression: characterization, signal transduction, and functional roles
M Ito - Physiological reviews, 2001 - journals.physiology.org
Cerebellar Purkinje cells exhibit a unique type of synaptic plasticity, namely, long-term
depression (LTD). When two inputs to a Purkinje cell, one from a climbing fiber and the other …
depression (LTD). When two inputs to a Purkinje cell, one from a climbing fiber and the other …
[HTML][HTML] Conformational motions and ligand-binding underlying gating and regulation in IP3R channel
Abstract Inositol-1, 4, 5-trisphosphate receptors (IP3Rs) are activated by IP3 and Ca2+ and
their gating is regulated by various intracellular messengers that finely tune the channel …
their gating is regulated by various intracellular messengers that finely tune the channel …
Ataxia and epileptic seizures in mice lacking type 1 inositol 1, 4, 5-trisphosphate receptor
M Matsumoto, T Nakagawa, T Inoue, E Nagata… - Nature, 1996 - nature.com
Abstract THE inositol 1, 4, 5-trisphosphate (InsP3) receptor acts as an InsP3-gated Ca2+
release channel in a variety of cell types1, 2. Type 1 InsP3 receptor (IP3R1) is the major …
release channel in a variety of cell types1, 2. Type 1 InsP3 receptor (IP3R1) is the major …
Giantin, a novel conserved Golgi membrane protein containing a cytoplasmic domain of at least 350 kDa.
AD Linstedt, HP Hauri - Molecular biology of the cell, 1993 - Am Soc Cell Biol
The Golgi complex consists of a series of stacked cisternae in most eukaryotes.
Morphological studies indicate the existence of intercisternal cross-bridge structures that …
Morphological studies indicate the existence of intercisternal cross-bridge structures that …
Cellular localization of a metabotropic glutamate receptor in rat brain
In rat brain, the cellular localization of a phosphoinositide-linked metabotropic glutamate
receptor (mGluR1α) was demonstrated using antibodies that recognize the C-terminus of the …
receptor (mGluR1α) was demonstrated using antibodies that recognize the C-terminus of the …
[HTML][HTML] Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1, 4, 5‐trisphosphate receptors in signal transduction through the B‐cell antigen receptor
H Sugawara, M Kurosaki, M Takata, T Kurosaki - The EMBO journal, 1997 - embopress.org
Stimulation of B‐cell antigen receptor (BCR) induces a rapid increase in cytoplasmic free
calcium due to its release from intracellular stores and influx from the extracellular …
calcium due to its release from intracellular stores and influx from the extracellular …