[HTML][HTML] The clinical, economic, and humanistic burden of Dravet syndrome–A systematic literature review

J Sullivan, AM Deighton, MC Vila, SM Szabo, B Maru… - Epilepsy & Behavior, 2022 - Elsevier
Dravet syndrome (DS) is a developmental and epileptic encephalopathy with evolving
disease course as individuals age. In recent years, the treatment landscape of DS has …

Consensus panel recommendations for the optimization of EPIDIOLEX® treatment for seizures associated with Lennox–Gastaut syndrome, Dravet syndrome, and …

RT Wechsler, DE Burdette, BE Gidal, A Hyslop… - Epilepsia …, 2024 - Wiley Online Library
Following the approval of Epidiolex®(cannabidiol; CBD) for the treatment of seizures
associated with Lennox–Gastaut syndrome (LGS), Dravet syndrome (DS), and tuberous …

Fenfluramine as antiseizure medication for epilepsy

M Gogou, JH Cross - Developmental Medicine & Child …, 2021 - Wiley Online Library
Fenfluramine hydrochloride has classically been described as acting pharmacologically
through a serotonergic mechanism. Therefore, it was initially used as an anorectic drug …

Progressive worsening of gait and motor abnormalities in older adults with Dravet syndrome

A Selvarajah, C Gorodetsky, P Marques, Q Zulfiqar Ali… - Neurology, 2022 - AAN Enterprises
Background and Objectives Relative to the pediatric population, there is limited information
about Dravet syndrome (DS) in adults. In addition to some of the gait abnormalities reported …

Functional mobility in children and young adults with Dravet syndrome

K Verheyen, L Wyers, E Lambrecht… - … Medicine & Child …, 2023 - Wiley Online Library
Aim This cohort study aimed to describe functional mobility in Dravet syndrome, a
developmental and epileptic encephalopathy. Method Functional mobility was assessed in …

Independent walking and cognitive development in preschool children with Dravet syndrome

K Verheyen, L Wyers, A Del Felice… - … Medicine & Child …, 2021 - Wiley Online Library
Aim To investigate the relation between cognitive and motor development in preschool aged
children with Dravet syndrome, in particular between the age of independent walking and …

Comorbidities in Dravet syndrome and Lennox–Gastaut syndrome

F Marchese, S Cappelletti, M Filippini, CA Guido… - SN Comprehensive …, 2021 - Springer
This study aims to describe the main cognitive and behavioral comorbidities of Dravet
syndrome (DS) and Lennox–Gastaut syndrome (LGS), their impact on the health-related …

Deconstructing Dravet syndrome neurocognitive development: A scoping review

M Bertuccelli, K Verheyen, A Hallemans, JW Sander… - …, 2021 - Wiley Online Library
Dravet syndrome (DS) is a rare severe epilepsy syndrome associated with slowed
psychomotor development and behavioral disorders from the second year onward in a …

The mechanics behind gait problems in patients with Dravet Syndrome

L Wyers, K Verheyen, B Ceulemans, AS Schoonjans… - Gait & Posture, 2021 - Elsevier
Abstract Background Dravet Syndrome (DS) is a developmental and epileptic
encephalopathy starting in infancy and characterised by treatment resistant epilepsy with …

Case report: Dravet syndrome, feeding difficulties and gastrostomy

LM Clayton, E Williams, S Balestrini… - Frontiers in …, 2022 - frontiersin.org
Dravet syndrome (DS) is a developmental and epileptic encephalopathy associated with
variants in the voltage-gated sodium channel alpha 1 subunit (SCN1A) gene in around 90 …