Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Astrocytes, one of the largest glial cell population in the central nervous system (CNS), play
a key function in several events of brain development and function, such as synapse …

The nucleus accumbens is a major input structure of the basal ganglia and integrates
information from cortical and limbic structures to mediate goal-directed behaviors. Chronic …

Astrocytes, a subtype of glial cells, come in variety of forms and functions. However,
overarching role of these cell is in the homeostasis of the brain, be that regulation of ions …

Recent work on glial cell physiology has revealed that glial cells, and astrocytes in
particular, are much more actively involved in brain information processing than previously …

Astrocyte pathology occurs in association with Alzheimer's disease (AD) and in brain
ageing, but is poorly characterised. We sought to define the detailed cellular pathology of …

Astrocytes are thought to play a variety of key roles in the adult brain, such as their
participation in synaptic transmission, in wound healing upon brain injury, and adult …

Over the last 15 years, the field of neuroscience has evolved toward recognizing the critical
role of astroglia in shaping neuronal synaptic activity and along with the pre-and …

Deactivation of glutamatergic signaling in the brain is mediated by glutamate uptake into glia
and neurons by glutamate transporters. Glutamate transporters are sodium-dependent …

Addiction is characterized as a chronic relapsing disorder whereby addicted individuals
persistently engage in drug seeking and use despite profound negative consequences. The …