Hyperbilirubinaemia, presenting as jaundice, is a ubiquitous and frequently benign
condition in newborn babies but is a leading cause of hospitalisation in the first week of life …

The plasma compartment has particular features regarding the nature and concentration of
low and high molecular weight thiols and oxidized derivatives. Plasma is relatively poor in …

Background & Aims Spinal muscular atrophy (SMA) is an autosomal recessive, childhood-
onset motor neuron disease. Onasemnogene abeparvovec (OA) is a gene therapy designed …

Metabolism of haem by-products such as bilirubin by humans and their gut microbiota is
essential to human health, as excess serum bilirubin can cause jaundice and even …

Over the last decade, studies have unraveled many aspects of endogenous production and
physiological functions of carbon monoxide (CO). The majority of endogenous CO is …

Background: Hyperbilirubinemia, or jaundice, is a life threatening disorder in newborns. It is
a multifactorial disorder with many symptoms. Generally, the physiological jaundice is the …

Results Twenty-one percent (449 of 2110) experienced early AKI. Early AKI was associated
with higher risk of death (adjusted odds ratio, 2.8; 95% confidence interval, 1.7 to 4.7) and …

Because chronic neuroinflammation is a hallmark of neurodegenerative diseases and
compromises neuron viability, it is imperative to discover pharmacologic targets to modulate …

Hyperbilirubinemia is one of the most common problems encountered in term newborns.
Historically, management guidelines were derived from studies on bilirubin toxicity in infants …

Background: Severe hyperbilirubinemia is the most common cause of neonatal readmission
to hospital in Canada even though, in the majority of cases, risk factors can be identified …