ROS homeostasis and metabolism: a dangerous liason in cancer cells
E Panieri, MM Santoro - Cell death & disease, 2016 - nature.com
Tumor cells harbor genetic alterations that promote a continuous and elevated production of
reactive oxygen species. Whereas such oxidative stress conditions would be harmful to …
reactive oxygen species. Whereas such oxidative stress conditions would be harmful to …
Arsenic and human health: genotoxicity, epigenomic effects, and cancer signaling
Arsenic is a well-known element because of its toxicity. Humans as well as plants and
animals are negatively affected by its exposure. Some countries suffer from high levels of …
animals are negatively affected by its exposure. Some countries suffer from high levels of …
SARS-CoV-2 nucleocapsid protein impairs stress granule formation to promote viral replication
ZQ Zheng, SY Wang, ZS Xu, YZ Fu, YY Wang - Cell Discovery, 2021 - nature.com
The newly emerging coronavirus SARS-CoV-2 causes severe lung disease and substantial
mortality. How the virus evades host defense for efficient replication is not fully understood …
mortality. How the virus evades host defense for efficient replication is not fully understood …
p62-containing, proteolytically active nuclear condensates, increase the efficiency of the ubiquitin–proteasome system
A Fu, V Cohen-Kaplan, N Avni… - Proceedings of the …, 2021 - National Acad Sciences
Degradation of a protein by the ubiquitin–proteasome system (UPS) is a multistep process
catalyzed by sequential reactions. Initially, ubiquitin is conjugated to the substrate in a …
catalyzed by sequential reactions. Initially, ubiquitin is conjugated to the substrate in a …
Genotoxic and epigenetic mechanisms in arsenic carcinogenicity
Arsenic is a human carcinogen with weak mutagenic properties that induces tumors through
mechanisms not yet completely understood. People worldwide are exposed to arsenic …
mechanisms not yet completely understood. People worldwide are exposed to arsenic …
Recent advances in arsenic research: significance of differential susceptibility and sustainable strategies for mitigation
T Sanyal, P Bhattacharjee, S Paul… - Frontiers in public …, 2020 - frontiersin.org
Arsenic contamination in drinking water and associated adverse outcomes are one of the
major health issues in more than 50 countries worldwide. The scenario is getting even more …
major health issues in more than 50 countries worldwide. The scenario is getting even more …
Arsenic trioxide induces oxidative stress, DNA damage, and mitochondrial pathway of apoptosis in human leukemia (HL-60) cells
Background Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia
(AML), which accounts for approximately 10% of all acute myloid leukemia cases. It is a …
(AML), which accounts for approximately 10% of all acute myloid leukemia cases. It is a …
Arsenic exposure and non-carcinogenic health effects
M Martínez-Castillo… - Human & …, 2021 - journals.sagepub.com
Inorganic arsenic (iAs) exposure is a serious health problem that affects more than 140
million individuals worldwide, mainly, through contaminated drinking water. Acute iAs …
million individuals worldwide, mainly, through contaminated drinking water. Acute iAs …
[PDF][PDF] Heavy metal biomarker: Fish behavior, cellular alteration, enzymatic reaction and proteomics approaches.
MK Sabullah, SA Ahmad, MY Shukor… - International Food …, 2015 - ifrj.upm.edu.my
Due to the latest industrial development, many dangerous chemicals have been released
directly or indirectly which resulted in the polluted water bodies. Water rehabilitation is an …
directly or indirectly which resulted in the polluted water bodies. Water rehabilitation is an …
Toxic effects of arsenic trioxide on spermatogonia are associated with oxidative stress, mitochondrial dysfunction, autophagy and metabolomic alterations
H Chen, G Liu, N Qiao, Z Kang, L Hu, J Liao… - Ecotoxicology and …, 2020 - Elsevier
Arsenic is a toxic metalloid that can cause male reproductive malfunctions and is widely
distributed in the environment. The aim of this study was to investigate the cytotoxicity of …
distributed in the environment. The aim of this study was to investigate the cytotoxicity of …