[HTML][HTML] Type 2 immunity in tissue repair and fibrosis

RL Gieseck III, MS Wilson, TA Wynn - Nature Reviews Immunology, 2018 - nature.com
Type 2 immunity is characterized by the production of IL-4, IL-5, IL-9 and IL-13, and this
immune response is commonly observed in tissues during allergic inflammation or infection …

Herbal medicine: biomolecular and clinical aspects

IFF Benzie, S Wachtel-Galor - 2011 - books.google.com
Responding to the increased popularity of herbal medicines and other forms of
complementary or alternative medicine world-wide, this reference reviews and evaluates …

Th17 cells in human disease

LA Tesmer, SK Lundy, S Sarkar… - Immunological reviews, 2008 - Wiley Online Library
Our understanding of the role of T cells in human disease is undergoing revision as a result
of the discovery of T‐helper 17 (Th17) cells, a unique CD4+ T‐cell subset characterized by …

IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer

MF Neurath, S Finotto - Cytokine & growth factor reviews, 2011 - Elsevier
IL-6 activates various cell types carrying the membrane bound IL-6R (classical IL-6
signaling) as well as IL-6R− gp130+ cells via the soluble IL-6R (IL-6 trans-signaling). IL-6 …

Increased frequency of dual-positive TH2/TH17 cells in bronchoalveolar lavage fluid characterizes a population of patients with severe asthma

C Irvin, I Zafar, J Good, D Rollins, C Christianson… - Journal of allergy and …, 2014 - Elsevier
Background TH 2 cells can further differentiate into dual-positive TH 2/TH 17 cells. The
presence of dual-positive TH 2/TH 17 cells in the airways and their effect on asthma severity …

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

Y Komiyama, S Nakae, T Matsuki, A Nambu… - The Journal of …, 2006 - journals.aai.org
IL-17 is a proinflammatory cytokine that activates T cells and other immune cells to produce
a variety of cytokines, chemokines, and cell adhesion molecules. This cytokine is …

Interleukin-17 family and IL-17 receptors

TA Moseley, DR Haudenschild, L Rose… - Cytokine & growth factor …, 2003 - Elsevier
Interleukin-17 (IL-17) is a pro-inflammatory cytokine secreted by activated T-cells. Recently
discovered related molecules are forming a family of cytokines, the IL-17 family. The …

Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses

S Nakae, Y Komiyama, A Nambu, K Sudo, M Iwase… - Immunity, 2002 - cell.com
Abstract Interleukin-17 (IL-17) is a proinflammatory cytokine produced by T cells. The
involvement of IL-17 in human diseases has been suspected because of its detection in sera …

Identification of an interleukin (IL)-25–dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion

PG Fallon, SJ Ballantyne, NE Mangan… - The Journal of …, 2006 - rupress.org
Type 2 immunity, which involves coordinated regulation of innate and adaptive immune
responses, can protect against helminth parasite infection, but may lead to allergy and …

IL-6 signal transduction and its physiological roles: the signal orchestration model

D Kamimura, K Ishihara, T Hirano - Reviews of physiology, biochemistry …, 2004 - Springer
Abstract Interleukin (IL)-6 is a pleiotropic cytokine that not only affects the immune system,
but also acts in other biological systems and many physiological events in various organs. In …