Idiopathic pulmonary fibrosis (IPF): an overview

SL Barratt, A Creamer, C Hayton… - Journal of clinical …, 2018 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterised by chronic,
progressive scarring of the lungs and the pathological hallmark of usual interstitial …

The tobacco smoke component, acrolein, as a major culprit in lung diseases and respiratory cancers: Molecular mechanisms of acrolein cytotoxic activity

P Hikisz, D Jacenik - Cells, 2023 - mdpi.com
Acrolein, a highly reactive unsaturated aldehyde, is a ubiquitous environmental pollutant
that seriously threatens human health and life. Due to its high reactivity, cytotoxicity and …

PROLIDASE: A Review from Discovery to its Role in Health and Disease

I Eni-Aganga, ZM Lanaghan… - Frontiers in Molecular …, 2021 - frontiersin.org
Prolidase (peptidase D), encoded by the PEPD gene, is a ubiquitously expressed cytosolic
metalloproteinase, the only enzyme capable of cleaving imidodipeptides containing C …

Blood biomarkers in idiopathic pulmonary fibrosis

J Guiot, C Moermans, M Henket, JL Corhay, R Louis - Lung, 2017 - Springer
Purpose Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal lung disease of
unknown origin whose incidence has been increasing over the latest decade partly as a …

Matrix metalloproteinases in acute lung injury: mediators of injury and drivers of repair

A Davey, DF McAuley… - European Respiratory …, 2011 - Eur Respiratory Soc
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) comprise a
spectrum of acute inflammatory pulmonary oedema resulting in refractory hypoxaemia in the …

[HTML][HTML] Molecularly imprinted polymer-based extended-gate field-effect transistor (EG-FET) chemosensor for selective determination of matrix metalloproteinase-1 …

K Bartold, Z Iskierko, P Borowicz, K Noworyta… - Biosensors and …, 2022 - Elsevier
A conducting molecularly imprinted polymer (MIP) film was integrated with an extended-gate
field-effect transistor (EG-FET) transducer to determine epitopes of matrix metalloproteinase …

Identification of the lipid biomarkers from plasma in idiopathic pulmonary fibrosis by Lipidomics

F Yan, Z Wen, R Wang, W Luo, Y Du, W Wang… - BMC Pulmonary …, 2017 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is an irreversible interstitial pulmonary
disease featured by high mortality, chronic and progressive course, and poor prognosis with …

[HTML][HTML] Inhibition of metalloproteinases in therapy for severe lung injury due to COVID-19

B Solun, Y Shoenfeld - Medicine in drug discovery, 2020 - Elsevier
Since its first appearance in December 2019 in the Chinese province of Wuhan, COVID-19
has spread rapidly throughout the world and poses a serious threat to public health. Acute …

Idiopathic pulmonary fibrosis: from epithelial injury to biomarkers-insights from the bench side

M Kolb, K Borensztajn, B Crestani, M Kolb - Respiration, 2014 - karger.com
Idiopathic pulmonary fibrosis (IPF) is the most frequent fibrotic diffuse parenchymal lung
disease. Its prognosis is devastating:> 50% of the patients die within 3 years after diagnosis …

Peripheral blood biomarkers in idiopathic pulmonary fibrosis

R Vij, I Noth - Translational Research, 2012 - Elsevier
In this article, we review the evidence for peripheral blood biomarkers in idiopathic
pulmonary fibrosis (IPF), a life-threatening fibrotic lung disease of unknown etiology. We …