Tumor genomic testing for> 4,000 men with metastatic castration-resistant prostate cancer in the phase III trial PROfound (Olaparib)

M Hussain, C Corcoran, C Sibilla, K Fizazi, F Saad… - Clinical Cancer …, 2022 - AACR
Purpose: Successful implementation of genomic testing in clinical practice is critical for
identification of men with metastatic castration-resistant prostate cancer (mCRPC) eligible …

[HTML][HTML] Prostate specific membrane antigen positron emission tomography in primary prostate cancer diagnosis: first-line imaging is afoot

J Jiao, J Zhang, Z Li, W Wen, C Cui, Q Zhang, J Wang… - Cancer Letters, 2022 - Elsevier
Prostate specific membrane antigen positron emission tomography (PSMA PET) is an
excellent molecular imaging technique for prostate cancer. Currently, PSMA PET for patients …

[HTML][HTML] Clinical outcomes and molecular profiling of advanced metastatic castration-resistant prostate cancer patients treated with 225Ac-PSMA-617 targeted alpha …

MJ van der Doelen, N Mehra, IM van Oort… - … Oncology: Seminars and …, 2021 - Elsevier
Introduction Targeted alpha-radiation therapy (TAT) with 225 Ac-labeled prostate-specific
membrane antigen (PSMA) ligands is a promising novel treatment option for metastatic …

Incorporating PSMA-targeting theranostics into personalized prostate cancer treatment: a multidisciplinary perspective

TSC Ng, X Gao, K Salari, DV Zlatev, P Heidari… - Frontiers in …, 2021 - frontiersin.org
Recent developments in prostate-specific membrane antigen (PSMA) targeted diagnostic
imaging and therapeutics (theranostics) promise to advance the management of primary …

Multiparametric bone MRI can improve CT-guided bone biopsy target selection in cancer patients and increase diagnostic yield and feasibility of next-generation …

R Donners, I Figueiredo, N Tunariu, M Blackledge… - European …, 2022 - Springer
Objectives To evaluate whether multiparametric bone MRI (mpBMRI) utilising a combination
of DWI signal, ADC and relative fat-fraction (rFF) can identify bone metastases, which …

Multiparametric bone MRI targeting aides lesion selection for CT-guided sclerotic bone biopsies in metastatic castrate resistant prostate cancer

R Donners, I Figueiredo, D Westaby, DM Koh… - Cancer Imaging, 2023 - Springer
Background Bone biopsies in metastatic castrate-resistant prostate cancer (mCRPC)
patients can be challenging. This study's objective was to prospectively validate a …

Optimising CT-guided biopsies of sclerotic bone lesions in cancer patients

R Donners, N Fotiadis, I Figueiredo, M Blackledge… - European …, 2022 - Springer
Objectives Investigate the laboratory, imaging and procedural factors that are associated
with a tumour-positive and/or NGS-feasible CT-guided sclerotic bone lesion biopsy result in …

Prostate-specific membrane antigen PET for assessment of primary and recurrent prostate cancer with histopathology as reference standard: a systematic review and …

E Hernes, ME Revheim, KH Hole, AJ Tulipan… - PET clinics, 2021 - pet.theclinics.com
Prostate-Specific Membrane Antigen PET for Assessment of Primary and Recurrent Prostate
Cancer with Histopathology as Reference Standard - PET Clinics Skip to Main Content …

CTC-Based Liquid Biopsies and Diagnostic Leukapheresis

NH Stoecklein - Circulating Tumor Cells: Advances in Liquid Biopsy …, 2023 - Springer
Circulating tumor cells (CTCs) appear as ideal tissue surrogate to inform on molecular
characteristics of systemic cancer for rational therapeutic decision-making. The full potential …

Prior PSMA PET-CT imaging and Hounsfield unit impact on tumor yield and success of molecular analyses from bone biopsies in metastatic prostate cancer

M Smits, K Ekici, S Pamidimarri Naga, IM van Oort… - Cancers, 2020 - mdpi.com
Simple Summary Prostate cancer is currently the fifth leading cause of death in men
worldwide. To personalize and guide treatment in prostate cancer, identification of …