Physiology of the cerebellum

E D'Angelo - Handbook of clinical neurology, 2018 - Elsevier
The cerebellum is a central brain structure deeply integrated into major loops with the
cerebral cortex, brainstem, and spinal cord. The cerebellum shows a complex regional …

Consensus paper: decoding the contributions of the cerebellum as a time machine. From neurons to clinical applications

M Bareš, R Apps, L Avanzino, A Breska, E D'Angelo… - The Cerebellum, 2019 - Springer
Time perception is an essential element of conscious and subconscious experience,
coordinating our perception and interaction with the surrounding environment. In recent …

Timing and plasticity in the cerebellum: focus on the granular layer

E D'Angelo, CI De Zeeuw - Trends in neurosciences, 2009 - cell.com
Two of the most striking properties of the cerebellum are its control in timing of motor
operations and its ability to adapt behavior to new sensorimotor associations. Here, we …

[HTML][HTML] Synaptic representation of locomotion in single cerebellar granule cells

K Powell, A Mathy, I Duguid, M Häusser - Elife, 2015 - elifesciences.org
The cerebellum plays a crucial role in the regulation of locomotion, but how movement is
represented at the synaptic level is not known. Here, we use in vivo patch-clamp recordings …

[HTML][HTML] A realistic large-scale model of the cerebellum granular layer predicts circuit spatio-temporal filtering properties

S Solinas, T Nieus, ED'Angelo - Frontiers in cellular neuroscience, 2010 - frontiersin.org
The way the cerebellar granular layer transforms incoming mossy fiber signals into new
spike patterns to be related to Purkinje cells is not yet clear. Here, a realistic computational …

P2 receptors and neuronal injury

H Franke, U Krügel, P Illes - Pflügers Archiv, 2006 - Springer
Abstract Extracellular adenosine 5′-triphosphate (ATP) was proposed to be an activity-
dependent signaling molecule that regulates glia–glia and glia–neuron communications …

[HTML][HTML] The cerebellar Golgi cell and spatiotemporal organization of granular layer activity

E D'Angelo, S Solinas, J Mapelli, D Gandolfi… - Frontiers in neural …, 2013 - frontiersin.org
The cerebellar granular layer has been suggested to perform a complex spatiotemporal
reconfiguration of incoming mossy fiber signals. Central to this role is the inhibitory action …

The spatial organization of long-term synaptic plasticity at the input stage of cerebellum

J Mapelli, E D'Angelo - Journal of Neuroscience, 2007 - Soc Neuroscience
The spatial organization of long-term synaptic plasticity [long-term potentiation (LTP) and
long-term depression (LTD)] is supposed to play a critical role for distributed signal …

The organization of plasticity in the cerebellar cortex: from synapses to control

E D'Angelo - Progress in brain research, 2014 - Elsevier
The cerebellum is thought to play a critical role in procedural learning, but the relationship
between this function and the underlying cellular and synaptic mechanisms remains largely …

Distributed circuit plasticity: new clues for the cerebellar mechanisms of learning

E D'Angelo, L Mapelli, C Casellato, JA Garrido… - The Cerebellum, 2016 - Springer
The cerebellum is involved in learning and memory of sensory motor skills. However, the
way this process takes place in local microcircuits is still unclear. The initial proposal, casted …