As an essential micronutrient, copper is required for a wide range of physiological processes
in virtually all cell types. Because the accumulation of intracellular copper can induce …

Copper is one of the most abundant basic transition metals in the human body. It takes part
in oxygen metabolism, collagen synthesis, and skin pigmentation, maintaining the integrity …

Skin cutaneous melanoma (SKCM, hereafter referred to as melanoma) is the most lethal
skin cancer with increasing incidence. Regulated cell death plays an important role in …

We know that blood plasma contains many proteins and also other components that bind
copper. The largest contributor to copper in the plasma is ceruloplasmin, which accounts for …

Copper (Cu) is an essential micronutrient required for the activity of redox‐active enzymes
involved in critical metabolic reactions, signaling pathways, and biological functions …

Cells require tight regulation of the intracellular redox balance and consequently of reactive
oxygen species for proper redox signaling and maintenance of metal (eg, of iron and …

Copper plays an essential role in normal human physiology. Copper misbalance affects
heart development, CNS and liver function, influences lipid metabolism, inflammation, and …

Essential trace elements play pivotal roles in numerous structural and catalytic functions of
proteins. Adequate intake of essential trace elements from the daily diet is indispensable to …

Studies of metal uptake, metabolism and excretion by single bacterial, yeast, plant and
animal cells is a widespread area of research, yet little is known about the reactivity and …

Albumin has a long historical involvement in design of media for the successful culture of
mammalian cells, in both the research and commercial fields. The potential application of …