Spermidine, a caloric restriction mimetic, provides neuroprotection against normal and d-galactose-induced oxidative stress and apoptosis through activation of …

S Singh, R Kumar, G Garg, AK Singh, AK Verma… - Biogerontology, 2021 - Springer
Spermidine (SPD) is a natural polyamine present in all living organisms and is involved in
the maintenance of cellular homeostasis by inducing autophagy in different model …

Reduced energy metabolism contributing to aging of skeletal muscle by serum metabolomics and gut microbiota analysis

P He, G Du, X Qin, Z Li - Life Sciences, 2023 - Elsevier
Aims Sarcopenia is an age-related syndrome characterized by a gradual loss of the muscle
mass, strength, and function. It is associated with a high risk of adverse consequences such …

Chitosan displays a potent caloric restriction mimetic effect in senescent rats

R Kumar, M Kumar, SI Rizvi - Rejuvenation Research, 2021 - liebertpub.com
Chitosan is a polysaccharide made up of β1, 4-linked d-glucosamine (GlcN) and N-acetyl-
GlcN. In this study, we evaluated the possible caloric restriction mimetic (CRM) effect of …

[HTML][HTML] Effects of Loofah cylindrica extract on learning and memory ability, brain tissue morphology, and immune function of aging mice

L Dong, C Liu - Open Life Sciences, 2021 - degruyter.com
In this study, we aimed to observe the effects of Loofah cylindrica (LC) extract on learning
and memory ability, brain tissue morphology, and immune function of aging mice. Kunming …

The effect of dolutegravir on adipose tissue health

JA Coetzee - 2022 - scholar.sun.ac.za
Introduction: Dolutegravir, an integrase strand transfer inhibitor (INSTI), forms part of the first-
line antiretroviral (ARV) therapy. Despite low cost, fewer drug-drug interactions and minimal …