Simple Summary Nephrotoxicity is the dose-limiting factor of cisplatin treatment.
Nephrotoxicity is characterized by reduced kidney function. Although an often-reversible …

Cisplatin is a platinum-based chemotherapeutic that has long since been effective against a
variety of solid-cancers, substantially improving the five-year survival rates for cancer …

To control the size of metal oxide nanoparticles, capping agents are often employed in the
green synthesis of metal oxide nanoparticles. To guide the role of phytochemical-based …

Oleanolic acid (OA) is a natural compound that possesses numerous beneficial health
effects, including anticancer activity. The current study aimed to investigate the role of …

Drug-induced nephrotoxicity (DIN) is a major cause of kidney damage and is associated
with high mortality and morbidity, which limits the clinical use of certain therapeutic or …

Aucubin is an iridoid glycoside widely spread in the families Cornaceae, Garryaceae,
Orobanchaceae, Globulariaceae, Eucommiaceae, Scrophulariaceae, Plantaginaceae, and …

Background Hepatic inflammation can substantially impact the development of acute
hepatitis. It is a pressing need to identify and exploit novel therapeutic targets as well as …

Cisplatin is commonly used to treat cancers and is associated with a significant risk of
irreversible sensorineural hearing loss. However, no effective preventive strategies are …

Rhoifolin (ROF) is a naturally occurring flavonoid compound with diverse pharmacological
and therapeutic benefits. The current investigation was designed to evaluate the curative …

Sinomenine is a pharmacologically active alkaloid with antioxidant and anti-inflammatory
properties. We aimed to investigate the mechanism of renoprotective activity of sinomenine …