The role of vitamin D in health and disease: A narrative review on the mechanisms linking vitamin D with disease and the effects of supplementation

E Rebelos, N Tentolouris, E Jude - Drugs, 2023 - Springer
Vitamin D insufficiency or deficiency (VDD) is a very prevalent condition in the general
population. Vitamin D is necessary for optimal bone mineralization, but apart from the bone …

Sunlight and Vitamin D: A global perspective for health

M Wacker, MF Holick - Dermato-endocrinology, 2013 - Taylor & Francis
Vitamin D is the sunshine vitamin that has been produced on this earth for more than 500
million years. During exposure to sunlight 7-dehydrocholesterol in the skin absorbs UV B …

Effect of monthly high-dose vitamin D supplementation on cardiovascular disease in the vitamin D assessment study: a randomized clinical trial

R Scragg, AW Stewart, D Waayer, CMM Lawes… - JAMA …, 2017 - jamanetwork.com
Importance Cohort studies have reported increased incidence of cardiovascular disease
(CVD) among individuals with low vitamin D status. To date, randomized clinical trials of …

A systematic review of vitamin D status in populations worldwide

J Hilger, A Friedel, R Herr, T Rausch, F Roos… - British journal of …, 2014 - cambridge.org
Vitamin D deficiency is associated with osteoporosis and is thought to increase the risk of
cancer and CVD. Despite these numerous potential health effects, data on vitamin D status …

Vitamin D deficiency and diabetes

MJ Berridge - Biochemical Journal, 2017 - portlandpress.com
Vitamin D deficiency has been linked to the onset of diabetes. This review summarizes the
role of Vitamin D in maintaining the normal release of insulin by the pancreatic beta cells (β …

Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data

L Rejnmark, LS Bislev, KD Cashman, G Eiríksdottir… - PloS one, 2017 - journals.plos.org
Background A large number of observational studies have reported harmful effects of low 25-
hydroxyvitamin D (25OHD) levels on non-skeletal outcomes. We performed a systematic …

Blood 25-hydroxy vitamin D levels and incident type 2 diabetes: a meta-analysis of prospective studies

Y Song, L Wang, AG Pittas, LC Del Gobbo… - Diabetes …, 2013 - Am Diabetes Assoc
OBJECTIVE To quantitatively assess the strength and shape of the association between
blood 25-hydroxy vitamin D [25 (OH) D] levels and incident risk of type 2 diabetes …

Vitamin D and type 2 diabetes

P Lips, M Eekhoff, N van Schoor, M Oosterwerff… - The Journal of steroid …, 2017 - Elsevier
Vitamin D deficiency is associated with a decreased insulin release, insulin resistance and
type 2 diabetes in experimental and epidemiological studies. Animal studies show that 1α …

The roles of vitamin D in skeletal muscle: form, function, and metabolism

CM Girgis, RJ Clifton-Bligh, MW Hamrick… - Endocrine …, 2013 - academic.oup.com
Beyond its established role in bone and mineral homeostasis, there is emerging evidence
that vitamin D exerts a range of effects in skeletal muscle. Reports of profound muscle …

Vitamin D deficiency and risk of cardiovascular disease

TJ Wang, MJ Pencina, SL Booth, PF Jacques… - Circulation, 2008 - Am Heart Assoc
Background—Vitamin D receptors have a broad tissue distribution that includes vascular
smooth muscle, endothelium, and cardiomyocytes. A growing body of evidence suggests …