Metals to combat antimicrobial resistance
Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …
Antibiotic resistance: The challenges and some emerging strategies for tackling a global menace
D Chinemerem Nwobodo, MC Ugwu… - Journal of clinical …, 2022 - Wiley Online Library
Background Antibiotic resistance is currently the most serious global threat to the effective
treatment of bacterial infections. Antibiotic resistance has been established to adversely …
treatment of bacterial infections. Antibiotic resistance has been established to adversely …
Antidepressants can induce mutation and enhance persistence toward multiple antibiotics
Antibiotic resistance is an urgent threat to global health. Antidepressants are consumed in
large quantities, with a similar pharmaceutical market share (4.8%) to antibiotics (5%). While …
large quantities, with a similar pharmaceutical market share (4.8%) to antibiotics (5%). While …
Microbiological insights into anaerobic digestion for biogas, hydrogen or volatile fatty acids (VFAs): a review
In the past decades, considerable attention has been directed toward anaerobic digestion
(AD), which is an effective biological process for converting diverse organic wastes into …
(AD), which is an effective biological process for converting diverse organic wastes into …
Biofilms as promoters of bacterial antibiotic resistance and tolerance
C Uruén, G Chopo-Escuin, J Tommassen… - Antibiotics, 2020 - mdpi.com
Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …
In vivo three-dimensional multispectral photoacoustic imaging of dual enzyme-driven cyclic cascade reaction for tumor catalytic therapy
S Lei, J Zhang, NT Blum, M Li, DY Zhang, W Yin… - Nature …, 2022 - nature.com
Non-invasive visualization of dynamic molecular events in real-time via molecular imaging
may enable the monitoring of cascade catalytic reactions in living systems, however effective …
may enable the monitoring of cascade catalytic reactions in living systems, however effective …
Clinically relevant mutations in core metabolic genes confer antibiotic resistance
Although metabolism plays an active role in antibiotic lethality, antibiotic resistance is
generally associated with drug target modification, enzymatic inactivation, and/or transport …
generally associated with drug target modification, enzymatic inactivation, and/or transport …
Potentiating hypoxic microenvironment for antibiotic activation by photodynamic therapy to combat bacterial biofilm infections
Traditional antibiotic treatment has limited efficacy for the drug-tolerant bacteria present in
biofilms because of their unique metabolic conditions in the biofilm infection …
biofilms because of their unique metabolic conditions in the biofilm infection …
Rescuing the last-line polymyxins: achievements and challenges
Antibiotic resistance is a major global health challenge and, worryingly, several key Gram
negative pathogens can become resistant to most currently available antibiotics. Polymyxins …
negative pathogens can become resistant to most currently available antibiotics. Polymyxins …
Genomic surveillance for antimicrobial resistance—a One Health perspective
Antimicrobial resistance (AMR)—the ability of microorganisms to adapt and survive under
diverse chemical selection pressures—is influenced by complex interactions between …
diverse chemical selection pressures—is influenced by complex interactions between …