The immune-inflammatory response is associated with increased nitro-oxidative stress. The
aim of this mechanistic review is to examine:(a) the role of redox-sensitive transcription …

Liver ischaemia–reperfusion injury (LIRI), a local sterile inflammatory response driven by
innate immunity, is one of the primary causes of early organ dysfunction and failure after …

Platelets are the primary cellular mediators of hemostasis and this function firmly acquaints
them with a variety of inflammatory processes. For example, platelets can act as circulating …

In traumatized patients, the primary cause of mortality is uncontrollable continuous bleeding
and unexpected intraoperative bleeding which is likely to increase the risk of complications …

In 2019 first reports about a new human coronavirus emerged, which causes common cold
symptoms as well as acute respiratory distress syndrome. The virus was identified as severe …

Vascular pathologies underpin and intertwine autoimmune rheumatic diseases and
cardiovascular conditions, and atherosclerosis is increasingly recognized as the leading …

Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are
based on a range of novel platforms, with adenovirus-based approaches (like ChAdOx1 …

Mounting evidence suggests that platelets play an essential role in cancer metastasis. The
interactions between platelets and circulating tumor cells (CTCs) promote cancer …

Until recently, the nucleic acid content of platelets was considered to be fully determined by
their progenitor megakaryocyte. However, it is now well understood that additional …

Background Research on neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio
(PLR), and monocyte-to-lymphocyte ratio (MLR) in depression is still emerging and has …