Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

HIV-associated cryptococcal meningitis is by far the most common cause of adult meningitis
in many areas of the world that have high HIV seroprevalence. In most areas in Sub …

Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

Fungi must meet four criteria to infect humans: growth at human body temperatures,
circumvention or penetration of surface barriers, lysis and absorption of tissue, and …

Cryptococcosis is a potentially lethal disease of humans/animals caused by Cryptococcus
neoformans and Cryptococcus gattii. Distinction between the two species is based on …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes approximately
625,000 deaths per year from nervous system infections. Here, we leveraged a unique …

Considerable progress in our understanding of yeast genomes and their evolution has been
made over the last decade with the sequencing, analysis, and comparisons of numerous …

The genus Cryptococcus contains two primary species complexes that are significant
opportunistic human fungal pathogens: C. neoformans and C. gattii. In humans …

Emerging infections caused by fungi have become a widely recognized global
phenomenon. Their notoriety stems from their causing plagues and famines, driving species …

Cryptococcosis is a major fungal disease caused by members of the Cryptococcus gattii and
Cryptococcus neoformans species complexes. After more than 15 years of molecular …