[HTML][HTML] Role of FGFR3 in bladder cancer: Treatment landscape and future challenges
CM Ascione, F Napolitano, D Esposito… - Cancer Treatment …, 2023 - Elsevier
Bladder cancer is a heterogeneous malignancy and is responsible for approximately 3.2%
of new diagnoses of cancer per year (Sung et al., 2021). Fibroblast Growth Factor Receptors …
of new diagnoses of cancer per year (Sung et al., 2021). Fibroblast Growth Factor Receptors …
The fibroblast growth factor signaling pathway
DM Ornitz, N Itoh - Wiley Interdisciplinary Reviews …, 2015 - Wiley Online Library
The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …
[HTML][HTML] Inhibition of the fibroblast growth factor receptor (FGFR) pathway: the current landscape and barriers to clinical application
YK Chae, K Ranganath, PS Hammerman, C Vaklavas… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The fibroblast growth factor/fibroblast growth factor receptor (FGF/FGFR) is a tyrosine kinase
signaling pathway that has a fundamental role in many biologic processes including …
signaling pathway that has a fundamental role in many biologic processes including …
Receptor specificity of the fibroblast growth factor family
DM Ornitz, J Xu, JS Colvin, DG McEwen… - Journal of Biological …, 1996 - ASBMB
Fibroblast growth factors (FGFs) are essential molecules for mammalian development. The
nine known FGF ligands and the four signaling FGF receptors (and their alternatively spliced …
nine known FGF ligands and the four signaling FGF receptors (and their alternatively spliced …
Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia
Achondroplasia(ACH) is the most common genetic form of dwarfism. This disorder is
inherited as an autosomal dominant trait, although the majority of cases are sporadic. A …
inherited as an autosomal dominant trait, although the majority of cases are sporadic. A …
Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity
D Schmucker, JC Clemens, H Shu, CA Worby, J Xiao… - Cell, 2000 - cell.com
A Drosophila homolog of human Down syndrome cell adhesion molecule (DSCAM), an
immunoglobulin superfamily member, was isolated by its affinity to Dock, an SH3/SH2 …
immunoglobulin superfamily member, was isolated by its affinity to Dock, an SH3/SH2 …
Biological roles of fibroblast growth factor-2
A Bikfalvi, S Klein, G Pintucci, DB Rifkin - Endocrine reviews, 1997 - academic.oup.com
Biological Roles of Fibroblast Growth Factor-2* | Endocrine Reviews | Oxford Academic
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[PDF][PDF] PROTEIN-TYROSINE KINASES AND THEIR SIGNAL TRANSDUCTION PATHWAYS
P Van der Geer, T Hunter - Annu. Rev. Cell Biol, 1994 - researchgate.net
Cells modulate their activities in response to signals from their surrounding environment.
Single cell organisms respond mainly to nutrient cues, many of which are able to cross the …
Single cell organisms respond mainly to nutrient cues, many of which are able to cross the …
Structural and functional diversity in the FGF receptor multigene family
DE Johnson, LT Williams - Advances in cancer research, 1992 - Elsevier
Publisher Summary The fibroblast growth factors (FGFs) constitute a family of closely related
polypeptide mitogens. There are seven members of this family, identified on the basis of …
polypeptide mitogens. There are seven members of this family, identified on the basis of …
α-Tanycytes of the adult hypothalamic third ventricle include distinct populations of FGF-responsive neural progenitors
SC Robins, I Stewart, DE McNay, V Taylor… - Nature …, 2013 - nature.com
Emerging evidence suggests that new cells, including neurons, can be generated within the
adult hypothalamus, suggesting the existence of a local neural stem/progenitor cell niche …
adult hypothalamus, suggesting the existence of a local neural stem/progenitor cell niche …