Oral submucous fibrosis: a review on etiopathogenesis, diagnosis, and therapy

YH Shih, TH Wang, TM Shieh, YH Tseng - International journal of …, 2019 - mdpi.com
Oral submucous fibrosis (OSF) is characterized by abnormal collagen deposition. It is a
precancerous disorder and transforms into a malignant tumor in 1.5–15% of all cases …

Oral submucous fibrosis: a review on biomarkers, pathogenic mechanisms, and treatments

YW Shen, YH Shih, LJ Fuh, TM Shieh - International journal of molecular …, 2020 - mdpi.com
Oral submucous fibrosis (OSF) is a collagen deposition disorder that affects a patient's oral
function and quality of life. It may also potentially transform into malignancy. This review …

miR-31 Ablates Expression of the HIF Regulatory Factor FIH to Activate the HIF Pathway in Head and Neck Carcinoma

CJ Liu, MM Tsai, PS Hung, SY Kao, TY Liu, KJ Wu… - Cancer research, 2010 - AACR
MicroRNAs (miRNA) are endogenously expressed noncoding RNAs with important
biological and pathological functions that are yet to be fully defined. This study investigated …

Increase of microRNA miR‐31 level in plasma could be a potential marker of oral cancer

CJ Liu, SY Kao, HF Tu, MM Tsai, KW Chang… - Oral …, 2010 - Wiley Online Library
Oral Diseases (2010) 16, 360–364 Backgrounds: Oral squamous cell carcinoma (OSCC) is
a worldwide disease. MicroRNAs are endogenously expressed non‐coding RNAs that have …

Evolving roles of lysyl oxidase family in tumorigenesis and cancer therapy

M Ye, Y Song, S Pan, M Chu, ZW Wang… - Pharmacology & …, 2020 - Elsevier
The lysyl oxidase (LOX) family is comprised of LOX and four LOX-like proteins (LOXL1,
LOXL2, LOXL3, and LOXL4), and mainly functions in the remodeling of extracellular matrix …

Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics

A Mammoto, T Mammoto, M Kanapathipillai… - Nature …, 2013 - nature.com
Increased vascular permeability contributes to many diseases, including acute respiratory
distress syndrome, cancer and inflammation. Most past work on vascular barrier function has …

The HIF-1–inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth

F Pez, F Dayan, J Durivault, B Kaniewski, G Aimond… - Cancer research, 2011 - AACR
Adaptation to hypoxia is a driving force for tumor progression that leads to therapy
resistance and poor clinical outcome. Hypoxic responses are mainly mediated by hypoxia …

Association between High miR-211 microRNA Expression and the Poor Prognosis of Oral Carcinoma

KW Chang, CJ Liu, TH Chu, HW Cheng… - Journal of dental …, 2008 - journals.sagepub.com
MicroRNAs (miRNAs) are non-coding RNAs that play roles in gene silencing and may be
involved in tumorigenesis. miR-211 was mapped to chromosome 15q13, a locus frequently …

Increased plasma circulating cell-free DNA could be a potential marker for oral cancer

LH Lin, KW Chang, SY Kao, HW Cheng… - International Journal of …, 2018 - mdpi.com
Background: Oral squamous cell carcinoma (OSCC) is a disease that affects patients
worldwide. DNA of dead cells is released into the blood stream and may be isolated from …

Sox2 expression involvement in the oncogenicity and radiochemoresistance of oral cancer stem cells

MY Chou, FW Hu, CH Yu, CC Yu - Oral oncology, 2015 - Elsevier
Objectives Sox2, a high-mobility-group DNA binding protein, is part of the key set of
transcription factors that are involved in the maintenance of pluripotency and self-renewal in …