[HTML][HTML] Jet injectors: Perspectives for small volume delivery with lasers

J Schoppink, DF Rivas - Advanced drug delivery reviews, 2022 - Elsevier
Needle-free jet injectors have been proposed as an alternative to injections with hypodermic
needles. Currently, a handful of commercial needle-free jet injectors already exist. However …

Recent advances in micro-and nano-scale carrier systems for controlled delivery of vaccines

EY Wang, M Sarmadi, B Ying, A Jaklenec, R Langer - Biomaterials, 2023 - Elsevier
Vaccines provide substantial safety against infectious diseases, saving millions of lives each
year. The recent COVID-19 pandemic highlighted the importance of vaccination in providing …

Vaccination into the dermal compartment: techniques, challenges, and prospects

J Hettinga, R Carlisle - Vaccines, 2020 - mdpi.com
In 2019, an 'influenza pandemic'and 'vaccine hesitancy'were listed as two of the top 10
challenges to global health by the WHO. The skin is a unique vaccination site, due to its …

Challenges and opportunities for small volumes delivery into the skin

M Mercuri, D Fernandez Rivas - Biomicrofluidics, 2021 - pubs.aip.org
Each individual's skin has its own features, such as strength, elasticity, or permeability to
drugs, which limits the effectiveness of one-size-fits-all approaches typically found in …

Development challenges of high concentration monoclonal antibody formulations

É Kollár, B Balázs, T Tari, I Siró - Drug Discovery Today: Technologies, 2020 - Elsevier
High concentration monoclonal antibody drug products represent a special segment of
biopharmaceuticals. In contrast to other monoclonal antibody products, high concentration …

Gas-particle flows in a microscale shock tube and collection efficiency in the jet impingement on a permeable surface

O Ejtehadi, TK Mankodi, I Sohn, BJ Kim, RS Myong - Physics of Fluids, 2023 - pubs.aip.org
We investigate the flow physics of non-equilibrium gases in interaction with solid particles in
a microscale shock tube and the collection efficiency in the jet impingement on a permeable …

Waterjet machining of biological tissues in medical surgeries: From soft tissue dissection to bone cutting

XF Song, J Zhao, H Yan, W Yu, L Yin - Journal of Manufacturing Processes, 2023 - Elsevier
Tissue cutting is a primary procedure in medical surgeries, during which waterjet machining
is increasingly used for tissue dissection, ablation and removal because it induces the least …

Advancements in transdermal drug delivery: A comprehensive review of physical penetration enhancement techniques

SS Gaikwad, AL Zanje, JD Somwanshi - International Journal of …, 2024 - Elsevier
Transdermal drug administration has grown in popularity in the pharmaceutical research
community due to its potential to improve drug bioavailability, compliance among patients …

Effect of contact angles on dynamical characteristics of the annular focused jet between parallel plates

J Huang, G Wang, Y Wang, J Wang, Z Yao - Physics of Fluids, 2022 - pubs.aip.org
Focused jets have been widely studied owing to the abundance of attractive flow
phenomena and industrial applications, whereas annular focused jets are less studied. This …

Mechanism and clinical applications of needle‐free injectors in dermatology: literature review

HS Han, JY Hong, TR Kwon, SE Lee… - Journal of Cosmetic …, 2021 - Wiley Online Library
Background Needle‐free jet injectors are devices that deliver drugs using a high‐speed jet
without a needle. Recent studies have significantly increased our understanding of the …