Conspectus Enzymes are desired catalysts for chemical synthesis, because they can be
engineered to provide unparalleled levels of efficiency and selectivity. Yet, despite the …

By integrating enzymatic catalysis with photocatalysis, photoenzymatic catalysis emerges as
a powerful strategy to enhance enzyme catalytic capabilities and provide superior …

Enzymes capable of assimilating fluorinated feedstocks are scarce. This situation poses a
challenge for the biosynthesis of fluorinated compounds used in pharmaceuticals …

Artificial photoenzymes with novel catalytic modes not found in nature are in high demand;
yet, they also present significant challenges in the field of biocatalysis. In this study, a …

Visible light-driven pyridoxal radical biocatalysis has emerged as a promising strategy for
the stereoselective synthesis of valuable noncanonical amino acids (ncAAs). Previously, the …

Alkene hydroalkylation enables efficient and selective formation of C (sp 3)–C (sp 3) bonds
with unique advantages, such as exceptional chemoselectivity and remarkable tolerance of …

The photoinduced unnatural reactions catalyzed by flavin-dependent enzymes usually
proceed through reduction pathways, which required the use of electron-sacrificial reagents …

The asymmetric cross-coupling of unsaturated bonds, hampered by their comparable
polarity and reactivity, as well as the scarcity of efficient catalytic systems capable of …

C–N bond formation is integral to modern chemical synthesis due to the ubiquity of nitrogen
heterocycles in small-molecule pharmaceuticals and agrochemicals. Alkene hydroamination …

In the field of biocatalysis, discovering novel reactivity from known enzymes has been a
longstanding challenge. Fatty acid photo‐decarboxylase from Chlorella variabilis (CvFAP) …