Over the past 15 years there has been an explosion of research on the dynamical properties
of proteins, largely driven by the emergence of a handful of techniques that are sensitive to …

RNase T1 is the best known representative of a large family of ribonucleolytic proteins
secreted by fungi, mostly Aspergillus and Penicillium species. Ribotoxins stand out among …

Gs (Geobacter sulfurreducens) can transfer electrons to the exterior of its cells, a property
that makes it a preferential candidate for the development of biotechnological applications …

The mite fungal pathogen Hirsutella thompsonii produces a single polypeptide chain,
insecticidal protein named hirsutellin A (HtA) that is composed of 130 amino acid residues …

Ribotoxins constitute a family of toxic extracellular fungal RNases that exert a highly specific
activity on a conserved region of the larger molecule of rRNA, known as the sarcin-ricin loop …

The three-dimensional structures of the α-sarcin ribotoxin and its Δ (7–22) deletion mutant,
both complexed with a 20-mer oligonucleotide mimicking the sarcin/ricin loop (SRL) of the …

Aspergillus fumigatus is responsible for many allergic respiratory diseases, the most notable
of which− due to its severity− is allergic bronchopulmonary aspergillosis. Aspf1 is a major …

Abstract The deletion mutant Δ (7‐22) of α‐sarcin, unlike its wild‐type protein counterpart,
lacks the specific ability to degrade rRNA in intact ribosomes and exhibits an increased …

The capsid protein of HIV‐1 (p24)(CA) forms the mature capsid of the human
immunodeficiency virus. Capsid assembly involves hexamerization of the N‐terminal …

α-Sarcin is an exquisitely specific ribonuclease that binds and cleaves a single
phosphodiester bond in the large rRNA of the eukaryotic ribosome, inactivating it. To better …