Discovery of non-squalene triterpenes

H Tao, L Lauterbach, G Bian, R Chen, A Hou, T Mori… - Nature, 2022 - nature.com
All known triterpenes are generated by triterpene synthases (TrTSs) from squalene or
oxidosqualene. This approach is fundamentally different from the biosynthesis of short-chain …

Antioxidant activity of natural hydroquinones

RM Giner, JL Ríos, S Máñez - Antioxidants, 2022 - mdpi.com
Secondary metabolites derived from hydroquinone are quite rare in nature despite the
original simplicity of its structure, especially when compared to other derivatives with which it …

Chemical ecology of marine sponges: new opportunities through “-omics”

VJ Paul, CJ Freeman, V Agarwal - Integrative and comparative …, 2019 - academic.oup.com
The chemical ecology and chemical defenses of sponges have been investigated for
decades; consequently, sponges are among the best understood marine organisms in terms …

The oxepane motif in marine drugs

H Barbero, C Díez-Poza, A Barbero - Marine Drugs, 2017 - mdpi.com
Oceans have shown to be a remarkable source of natural products. The biological
properties of many of these compounds have helped to produce great advances in …

Combinatory biosynthesis of prenylated 4-hydroxybenzoate derivatives by overexpression of the substrate-promiscuous prenyltransferase XimB in engineered E. coli

BB He, XL Bu, T Zhou, SM Li, MJ Xu, J Xu - ACS Synthetic Biology, 2018 - ACS Publications
Prenylated aromatic compounds are important intermediates in the biosynthesis of bioactive
molecules such as 3-chromanols from plants, ubiquinones from prokaryotes and …

Mass spectrometry-based integration and expansion of the chemical diversity harbored within a marine sponge

TP Cantrell, CJ Freeman, VJ Paul… - Journal of the …, 2019 - ACS Publications
Marine sponges and their associated symbionts produce a structurally diverse and complex
set of natural products including alkaloids, terpenoids, peptides, lipids, and steroids. A single …

Biomimetic total syntheses of chromane meroterpenoids, guadials B and C, guapsidial A and psiguajadial D

DH Dethe, V Kumar, R Maiti - Organic & Biomolecular Chemistry, 2018 - pubs.rsc.org
The first biomimetic total syntheses of chromane meroterpenoids, guadials B and C,
guapsidial A and psiguajadial D have been completed. The key synthetic transformation …

Calyxaprenols AD, New Merohexaprenoid Metabolites from the Marine Sponge Calyx sp.

CK Kim, KR Gustafson - Natural Product Sciences, 2020 - koreascience.kr
Four new merohexapenoids named calyxaprenols AD (1-4), together with the known
compound haliclotriol A (5), have been isolated from the marine sponge Calyx sp. which …

[PDF][PDF] KAJIAN BIOAKTIVITAS ANTIBAKTERI DAN SENYAWA METABOLIT SEKUNDER SPONS LAUT Haliclona sp., DARI PERAIRAN TANJUNG TIRAM MORAMO …

S Laut - academia.edu
Spons merupakan salah satu komponen organisme penyusun terumbu karang yang
menghasilkan senyawa metabolit sekunder dan mempunyai potensi yang belum banyak …

Chemical Ecology of Marine Sponges

VJ Paul, CJ Freeman, V Agarwal - Integrative and Comparative Biology, 2019 - JSTOR
The chemical ecology and chemical defenses of sponges have been investigated for
decades; consequently, sponges are among the best understood marine organisms in terms …