[HTML][HTML] Lung microbiome: new insights into the pathogenesis of respiratory diseases
The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …
Hypersensitivity pneumonitis: Current concepts in pathogenesis, diagnosis, and treatment
Hypersensitivity pneumonitis is an immune‐mediated interstitial lung disease caused by an
aberrant response to an inhaled exposure, which results in mostly T cell–mediated …
aberrant response to an inhaled exposure, which results in mostly T cell–mediated …
[HTML][HTML] Immuno-proteomic profiling reveals aberrant immune cell regulation in the airways of individuals with ongoing post-COVID-19 respiratory disease
B Vijayakumar, K Boustani, PP Ogger, A Papadaki… - Immunity, 2022 - cell.com
Some patients hospitalized with acute COVID-19 suffer respiratory symptoms that persist for
many months. We delineated the immune-proteomic landscape in the airways and …
many months. We delineated the immune-proteomic landscape in the airways and …
[HTML][HTML] Enhanced IL-1β release following NLRP3 and AIM2 inflammasome stimulation is linked to mtROS in airway macrophages in pulmonary fibrosis
A Trachalaki, E Tsitoura, S Mastrodimou… - Frontiers in …, 2021 - frontiersin.org
Fibrotic Interstitial lung diseases (ILDs) are complex disorders of variable clinical behaviour.
The majority of them cause significant morbidity, whilst Idiopathic Pulmonary Fibrosis (IPF) is …
The majority of them cause significant morbidity, whilst Idiopathic Pulmonary Fibrosis (IPF) is …
[HTML][HTML] S100A12 as biomarker of disease severity and prognosis in patients with idiopathic pulmonary fibrosis
Y Li, Y He, S Chen, Q Wang, Y Yang, D Shen… - Frontiers in …, 2022 - frontiersin.org
Background Idiopathic pulmonary fibrosis (IPF) is one of interstitial lung diseases (ILDs) with
poor prognosis. S100 calcium binding protein A12 (S100A12) has been reported as a …
poor prognosis. S100 calcium binding protein A12 (S100A12) has been reported as a …
[HTML][HTML] Pharmacomicrobiology of methotrexate in rheumatoid arthritis: gut microbiome as predictor of therapeutic response
H Yan, R Su, H Xue, C Gao, X Li, C Wang - Frontiers in Immunology, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a disabling autoimmune disease with invasive arthritis as the
main manifestation and synovitis as the basic pathological change, which can cause …
main manifestation and synovitis as the basic pathological change, which can cause …
Genetic risk factors for idiopathic pulmonary fibrosis: insights into immunopathogenesis
JE Michalski, DA Schwartz - Journal of Inflammation Research, 2021 - Taylor & Francis
Idiopathic pulmonary fibrosis is an etiologically complex interstitial lung disease
characterized by progressive scarring of the lungs with a subsequent decline in lung …
characterized by progressive scarring of the lungs with a subsequent decline in lung …
[HTML][HTML] The epithelial-immune crosstalk in pulmonary fibrosis
T Planté-Bordeneuve, C Pilette, A Froidure - Frontiers in immunology, 2021 - frontiersin.org
Interactions between the lung epithelium and the immune system involve a tight regulation
to prevent inappropriate reactions and have been connected to several pulmonary diseases …
to prevent inappropriate reactions and have been connected to several pulmonary diseases …
[HTML][HTML] Lung microbiome in idiopathic pulmonary fibrosis and other interstitial lung diseases
Interstitial lung diseases represent a heterogeneous and wide group of diseases in which
factors leading to disease initiation and progression are not fully understood. Recent …
factors leading to disease initiation and progression are not fully understood. Recent …
[HTML][HTML] Horizontal transmission of gut microbiota attenuates mortality in lung fibrosis
SJ Gurczynski, JH Lipinski, J Strauss, S Alam… - JCI insight, 2024 - ncbi.nlm.nih.gov
Pulmonary fibrosis is a chronic and often fatal disease. The pathogenesis is characterized
by aberrant repair of lung parenchyma, resulting in loss of physiological homeostasis …
by aberrant repair of lung parenchyma, resulting in loss of physiological homeostasis …