The members of the Management and Therapy Subcommittee undertook an evidence-
based review of current dry eye therapies and management options. Management options …

The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye
disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears …

The core mechanism of dry eye is the tear film instability. Tear film-oriented diagnosis
(TFOD) is a concept to clarify the cause of tear film instability by tear film, and tear film …

The 2017 consensus report of the Asia Dry Eye Society (ADES) on the definition and
diagnosis of dry eyes described dry eye disease as “Dry eye is a multifactorial disease …

The precorneal tear film is a complex mixture of proteins, lipids, metabolites, and electrolytes
with different structures and functionalities. Sustainable production of each tear component …

Publication of the DEWS report in 2007 established the state of the science of dry eye
disease (DED). Since that time, new evidence suggests that a rethinking of traditional …

Human cornea is covered by an aqueous tear film, and the outermost layer of the tear film is
coated by lipids. This so-called tear film lipid layer (TFLL) reduces surface tension of the tear …

The aim of the subcommittee report was to review published evidence describing tear film
changes secondary to contact lens wear and to examine the evidence for associations …

Components of the ocular surface synergistically contribute to maintaining and protecting a
smooth refractive layer to facilitate the optimal transmission of light. At the air–water …

Mucus is a hydrogel that constitutes the first innate defense in all mammals. The main
organic component of mucus, gel-forming mucins, forms a complex network through both …