The outer retina is nourished from the choroid, a capillary bed just inside the sclera. O2,
glucose, and other nutrients diffuse out of the choroid and then filter through a monolayer of …

The benefits of exercise to human health have long been recognised. However, only in the
past decade have researchers started to discover the molecular benefits that exercise …

In retinitis pigmentosa (RP), one of many possible genetic mutations causes rod
degeneration, followed by cone secondary death leading to blindness. Accumulating …

Glaucoma etiology often includes retinal ganglion cell (RGC) death associated with elevated
intraocular pressure (IOP). However, even when IOP is managed well, disease can …

Stem cell therapy for retinal degenerative diseases has been extensively tested in
preclinical and clinical studies. However, preclinical studies performed in animal models at …

Purpose: We aimed to explore differences in the NaIO 3-elicited responses of retinal
pigment epithelium (RPE) and other retinal cells associated with mouse strains and dosing …

Purpose: Maintaining levels of nicotinamide adenine dinucleotide (NAD+), a coenzyme
critical for cellular energetics and biosynthetic pathways, may be therapeutic in retinal …

In the field of eye health, the profound impact of exercise and physical activity on various
ocular diseases has become a focal point of attention. This review summarizes and …

Pre-mRNA processing factors (PRPFs) are vital components of the spliceosome and are
involved in the physiological process necessary for pre-mRNA splicing to mature mRNA. As …

Exercise is an effective neuroprotective intervention that preserves retinal function and
structure in several animal models of retinal degeneration. However, the retinal cell types …