Role of lipids and lipid metabolism in prostate cancer progression and the tumor's immune environment

A Siltari, H Syvälä, YR Lou, Y Gao, TJ Murtola - Cancers, 2022 - mdpi.com
Simple Summary Cholesterol, lipids, and lipid metabolism are important in prostate cancer.
Lipid metabolism interacts with androgens which are of clear importance in prostate cancer …

The tangled web of dyslipidemia and cancer: Is there any association?

S Neshat, A Rezaei, A Farid, R Sarallah… - Journal of Research …, 2022 - journals.lww.com
Cancer is a primary cause of mortality around the world and imposes a significant
physiological, psychological, and financial burden on patients. Lipids regulate cell cycle …

Plasma total cholesterol concentration and risk of higher‐grade prostate cancer: A nested case‐control study and a dose‐response meta‐analysis

H Liu, IM Shui, NN Keum, X Shen, K Wu… - … Journal of Cancer, 2023 - Wiley Online Library
Our previous publication found an increased risk of higher‐grade (Gleason sum≥ 7)
prostate cancer for men with high total cholesterol concentration (≥ 200 mg/dl) in the Health …

MBTPS2 acts as a regulator of lipogenesis and cholesterol synthesis through SREBP signalling in prostate cancer

AJ Tibbo, A Hartley, R Vasan, R Shaw… - British Journal of …, 2023 - nature.com
Background Prostate cancer is the most common cancer in men in the developed world, with
most deaths caused by advanced and metastatic disease which has no curative options …

Research progress of metabolomics in cervical cancer

Y Jia, K Zou, L Zou - European Journal of Medical Research, 2023 - Springer
Introduction Cervical cancer threatens women's health seriously. In recent years, the
incidence of cervical cancer is on the rise, and the age of onset tends to be younger …

Relationship between cholesterol-related lipids and severe acute pancreatitis: From bench to bedside

X Zhou, S Jin, J Pan, Q Lin, S Yang, Y Lu… - Journal of Clinical …, 2023 - mdpi.com
Highlights What are the main finding? Higher serum levels of total cholesterol and low-
density lipoprotein cholesterol are associated with the severity of AP, while the persistent …

Alteration of lipid metabolism in prostate cancer: multifaceted oncologic implications

M Zeković, U Bumbaširević, M Živković… - International Journal of …, 2023 - mdpi.com
Cancer is increasingly recognized as an extraordinarily heterogeneous disease featuring an
intricate mutational landscape and vast intra-and intertumor variability on both genetic and …

Proteogenomic characterization identifies clinical subgroups in EGFR and ALK wild-type never-smoker lung adenocarcinoma

H Kim, W Lee, Y Kim, SJ Lee, W Choi, GK Lee… - … & Molecular Medicine, 2024 - nature.com
Patients with lung adenocarcinoma who have never smoked (NSLA) and lack key driver
mutations, such as those in the EGFR and ALK genes, face limited options for targeted …

Revealing the role of alternariol in the local steroidogenesis in human prostate normal and cancer cells

KA Urbanek, K Kowalska… - International Journal of …, 2023 - mdpi.com
The mycotoxin alternariol (AOH) can be found in food products infected by Alternaria spp.
and is considered an endocrine-disruptive mycotoxin. The main mechanism of AOH toxicity …

Statin use and mortality risk in Asian patients with prostate cancer receiving androgen deprivation therapy: A population‐based cohort study

YHA Lee, JSK Chan, JMH Hui, P Tang, K Liu… - Cancer …, 2024 - Wiley Online Library
Background This study aimed to examine the associations between the use of statins
concurrent with androgen deprivation therapy (ADT) and the risks of mortality in Asian …