Microfluidic models of vascular functions
In vitro studies of vascular physiology have traditionally relied on cultures of endothelial
cells, smooth muscle cells, and pericytes grown on centimeter-scale plates, filters, and flow …
cells, smooth muscle cells, and pericytes grown on centimeter-scale plates, filters, and flow …
The flow of anisotropic nanoparticles in solution and in blood
The alignment of anisotropic nanoparticles in flow has been used for a range of applications
such as the preparation of strong fibres and the assembly of in‐plane aligned 1D …
such as the preparation of strong fibres and the assembly of in‐plane aligned 1D …
Do-it-yourself in vitro vasculature that recapitulates in vivo geometries for investigating endothelial-blood cell interactions
RG Mannino, DR Myers, B Ahn, Y Wang, M Rollins… - Scientific reports, 2015 - nature.com
Investigating biophysical cellular interactions in the circulation currently requires choosing
between in vivo models, which are difficult to interpret due in part to the hemodynamic and …
between in vivo models, which are difficult to interpret due in part to the hemodynamic and …
Microfluidic blood vasculature replicas using backside lithography
Blood vessels in living tissues are an organized and hierarchical network of arteries,
arterioles, capillaries, veinules and veins. Their sizes, lengths, shapes and connectivity are …
arterioles, capillaries, veinules and veins. Their sizes, lengths, shapes and connectivity are …
[HTML][HTML] 3D microvascular model recapitulates the diffuse large B-cell lymphoma tumor microenvironment in vitro
Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer that affects∼ 22 000
people in the United States yearly. Understanding the complex cellular interactions of the …
people in the United States yearly. Understanding the complex cellular interactions of the …
[HTML][HTML] Non-planar PDMS microfluidic channels and actuators: A review
Y Hwang, RN Candler - Lab on a Chip, 2017 - pubs.rsc.org
This review examines the state of the art for manufacturing non-planar miniature channels
and actuators from PDMS, where non-planar structures are defined here as those beyond …
and actuators from PDMS, where non-planar structures are defined here as those beyond …
[HTML][HTML] Particle margination and its implications on intravenous anticancer drug delivery
Abstract “Margination” refers to the movement of particles in flow toward the walls of a
channel. The term was first coined in physiology for describing the behavior of white blood …
channel. The term was first coined in physiology for describing the behavior of white blood …
Microfluidic device for sheathless particle focusing and separation using a viscoelastic fluid
Continuous sheathless particle separation with high efficiency is essential for various
applications such as biochemical analyses and clinical diagnosis. Here, a novel microfluidic …
applications such as biochemical analyses and clinical diagnosis. Here, a novel microfluidic …
Biofabrication strategies for creating microvascular complexity
Abstract Design and fabrication of effective biomimetic vasculatures constitutes a relevant
and yet unsolved challenge, lying at the heart of tissue repair and regeneration strategies …
and yet unsolved challenge, lying at the heart of tissue repair and regeneration strategies …
[HTML][HTML] Spontaneous oscillations of capillary blood flow in artificial microvascular networks
Previous computational studies have suggested that the capillary blood flow oscillations
frequently observed in vivo can originate spontaneously from the non-linear rheological …
frequently observed in vivo can originate spontaneously from the non-linear rheological …