Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models

I Guzmán-Soto, C McTiernan, M Gonzalez-Gomez… - Iscience, 2021 - cell.com
Biofilm formation in living organisms is associated to tissue and implant infections, and it has
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …

Approaches to dispersing medical biofilms

D Fleming, KP Rumbaugh - Microorganisms, 2017 - mdpi.com
Biofilm-associated infections pose a complex problem to the medical community, in that
residence within the protection of a biofilm affords pathogens greatly increased tolerances to …

[HTML][HTML] The staphylococcal exopolysaccharide PIA–Biosynthesis and role in biofilm formation, colonization, and infection

HTT Nguyen, TH Nguyen, M Otto - Computational and Structural …, 2020 - Elsevier
Exopolysaccharide is a key part of the extracellular matrix that contributes to important
mechanisms of bacterial pathogenicity, most notably biofilm formation and immune evasion …

Strategy to combat biofilms: a focus on biofilm dispersal enzymes

S Wang, Y Zhao, AP Breslawec, T Liang… - npj Biofilms and …, 2023 - nature.com
Bacterial biofilms, which consist of three-dimensional extracellular polymeric substance
(EPS), not only function as signaling networks, provide nutritional support, and facilitate …

Targeting biofilms therapy: current research strategies and development hurdles

Y Jiang, M Geng, L Bai - Microorganisms, 2020 - mdpi.com
Biofilms are aggregate of microorganisms in which cells are frequently embedded within a
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …

Signals, regulatory networks, and materials that build and break bacterial biofilms

E Karatan, P Watnick - Microbiology and molecular biology …, 2009 - Am Soc Microbiol
Biofilms are communities of microorganisms that live attached to surfaces. Biofilm formation
has received much attention in the last decade, as it has become clear that virtually all types …

Current and recent advanced strategies for combating biofilms

M Sadekuzzaman, S Yang… - … Reviews in Food …, 2015 - Wiley Online Library
Biofilms are matrix‐enclosed microbial aggregates that adhere to a biological or
nonbiological surface. Biofilm formation is a significant problem in the medical, food, and …

Update on Actinobacillus pleuropneumoniae—knowledge, gaps and challenges

EL Sassu, JT Bossé, TJ Tobias… - Transboundary and …, 2018 - Wiley Online Library
Porcine pleuropneumonia, caused by the bacterial porcine respiratory tract pathogen
Actinobacillus pleuropneumoniae, leads to high economic losses in affected swine herds in …

Differential Roles of Poly-N-Acetylglucosamine Surface Polysaccharide and Extracellular DNA in Staphylococcus aureus and Staphylococcus epidermidis Biofilms

EA Izano, MA Amarante, WB Kher… - Applied and …, 2008 - Am Soc Microbiol
Staphylococcus aureus and Staphylococcus epidermidis are major human pathogens of
increasing importance due to the dissemination of antibiotic-resistant strains. Evidence …

The pgaABCD Locus of Acinetobacter baumannii Encodes the Production of Poly-β-1-6-N-Acetylglucosamine, Which Is Critical for Biofilm Formation

AHK Choi, L Slamti, FY Avci, GB Pier… - Journal of …, 2009 - Am Soc Microbiol
We found that Acinetobacter baumannii contains a pgaABCD locus that encodes proteins
that synthesize cell-associated poly-β-(1-6)-N-acetylglucosamine (PNAG). Both a mutant …