Natural products have been a rich source of compounds for drug discovery. However, their
use has diminished in the past two decades, in part because of technical barriers to …

Drug of abuse (DOA) consumption is a growing problem worldwide, particularly with
increasing numbers of new psychoactive substances (NPS) entering the drug market …

A better understanding of human metabolism and its relationship with diseases is an
important task in human systems biology studies. In this paper, we present a high‐quality …

Xenobiotic metabolism, a ubiquitous natural response to foreign compounds, elicits initiating
signals for many pathophysiological events. Currently, most widely used techniques for …

The pathophysiological changes associated with Alzheimer's Disease (AD) begin decades
before the emergence of clinical symptoms. Understanding the early mechanisms …

BACKGROUND Metabolomics is a valuable tool with applications in almost all life science
areas. There is an increasing awareness of the essential need for high-quality biospecimens …

Advances in analytical methodologies, principally nuclear magnetic resonance
spectroscopy (NMR) and mass spectrometry (MS), during the last decade have made large …

Metabolomics approaches provide an analysis of changing metabolite levels in biological
samples. In the past decade, technical advances have spurred the application of …

In recent years, metabolomics developed to an accepted and valuable tool in life sciences.
Substantial improvements of analytical hardware allow metabolomics to run routinely now …

Metabonomics aims at the comprehensive and quantitative analysis of wide arrays of
metabolites in biological samples. It has shown particular promise in the areas of toxicology …