Benzophenone: A ubiquitous scaffold in medicinal chemistry
K Surana, B Chaudhary, M Diwaker, S Sharma - MedChemComm, 2018 - pubs.rsc.org
The benzophenone scaffold represents a ubiquitous structure in medicinal chemistry
because it is found in several naturally occurring molecules which exhibit a variety of …
because it is found in several naturally occurring molecules which exhibit a variety of …
In silico identification of novel benzophenone–coumarin derivatives as SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitors
In this study, we propose our novel benzophenone–coumarin derivatives (BCDs) as potent
inhibitors of the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2 virus, one of the …
inhibitors of the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2 virus, one of the …
Design, synthesis and molecular docking of benzophenone conjugated with oxadiazole sulphur bridge pyrazole pharmacophores as anti inflammatory and analgesic …
AR Gulnaz, YHE Mohammed, SA Khanum - Bioorganic Chemistry, 2019 - Elsevier
The prostaglandins (PG) a group of physiologically active lipid compounds having diverse
hormone like effects are important mediators of the body's response to pain and …
hormone like effects are important mediators of the body's response to pain and …
Polyphenols with Antiulcerogenic Action from Aqueous Decoction of Mango Leaves (Mangifera indica L.)
This study was designed to determine the gastroprotective effect of a Mangifera indica leaf
decoction (AD), on different experimental models in rodents. The administration of AD up to …
decoction (AD), on different experimental models in rodents. The administration of AD up to …
Fragment-based design, docking, synthesis, biological evaluation and structure–activity relationships of 2-benzo/benzisothiazolimino-5-aryliden-4-thiazolidinones as …
P Eleftheriou, A Geronikaki, D Hadjipavlou-Litina… - European journal of …, 2012 - Elsevier
Balanced modulation of several targets is one of the current strategies for the treatment of
multi-factorial diseases. Based on the knowledge of inflammation mechanisms, it was …
multi-factorial diseases. Based on the knowledge of inflammation mechanisms, it was …
Synthesis and biological activity of new anti-inflammatory compounds containing the 1, 4-benzodioxine and/or pyrrole system
Y Harrak, G Rosell, G Daidone, S Plescia… - Bioorganic & medicinal …, 2007 - Elsevier
A series of substituted derivatives containing the 1, 4-benzodioxine or pyrrole nucleus are
described. All the newly synthesized compounds were examined for their in vitro and in vivo …
described. All the newly synthesized compounds were examined for their in vitro and in vivo …
Selectivity in the photo-Fries rearrangement of some aryl benzoates in green and sustainable media. Preparative and mechanistic studies
Irradiation of a series of p-substituted aryl benzoates under N2 atmosphere in homogeneous
and micellar media was investigated by means of steady-state condition and of time …
and micellar media was investigated by means of steady-state condition and of time …
Design, synthesis, and anticancer evaluation of benzophenone derivatives bearing naphthalene moiety as novel tubulin polymerization inhibitors
G Wang, W Liu, J Tang, X Ma, Z Gong, Y Huang, Y Li… - Bioorganic …, 2020 - Elsevier
A series of benzophenone derivatives bearing naphthalene moiety were designed,
synthesized, characterized by 1 H NMR, 13 C NMR, and HRMS and evaluated for their …
synthesized, characterized by 1 H NMR, 13 C NMR, and HRMS and evaluated for their …
Synthesis, characterization and antibacterial activity of 2-[1-(5-chloro-2-methoxy-phenyl)-5-methyl-1H-pyrazol-4-yl]-5-(substituted-phenyl)-[1, 3, 4] oxadiazoles
NP Rai, VK Narayanaswamy, S Shashikanth… - European journal of …, 2009 - Elsevier
In the present investigation a series of novel 2-[1-(5-chloro-2-methoxy-phenyl)-5-methyl-1H-
pyrazol-4-yl]-5-(substituted-phenyl)-[1, 3, 4] oxadiazoles (4a–j) were synthesized by …
pyrazol-4-yl]-5-(substituted-phenyl)-[1, 3, 4] oxadiazoles (4a–j) were synthesized by …
Copper (II) complexes of salicylaldehydes and 2-hydroxyphenones: synthesis, structure, thermal decomposition study and interaction with calf-thymus DNA and …
A Zianna, G Psomas, A Hatzidimitriou… - RSC Advances, 2015 - pubs.rsc.org
The neutral mononuclear copper (II) complexes with substituted salicylaldehyde (X-saloH),
or 2-hydroxyphenone (ketoH) ligands, having the formula [Cu (L) 2 (S) n](where S= solvent …
or 2-hydroxyphenone (ketoH) ligands, having the formula [Cu (L) 2 (S) n](where S= solvent …