Heart Failure—Do We Need New Drugs or Have Them Already? A Case of Coenzyme Q10
KJ Filipiak, S Surma, M Romańczyk… - Journal of cardiovascular …, 2022 - mdpi.com
Heart failure (HF) is a global epidemic that contributes to the deterioration of quality of life
and its shortening in 1–3% of adult people in the world. Pharmacotherapy of HF should rely …
and its shortening in 1–3% of adult people in the world. Pharmacotherapy of HF should rely …
Combining idebenone and rosuvastatin prevents atherosclerosis by suppressing oxidative stress and NLRP3 inflammasome activation
W Yu, W Jiang, W Wu, G Wang, D Zhao, C Yan… - European Journal of …, 2023 - Elsevier
Atherosclerosis is a progressive inflammatory disease activated by excessive oxidized low-
density lipoprotein (ox-LDL). Statins are the first-line choice to reduce the risk of …
density lipoprotein (ox-LDL). Statins are the first-line choice to reduce the risk of …
Prospects of Intravenous Coenzyme Q10 Administration in Emergency Ischemic Conditions
EI Kalenikova, EA Gorodetskaya, OV Povarova… - Life, 2024 - mdpi.com
Coenzyme CoQ10 (CoQ10) is an endogenous lipid-soluble antioxidant that effectively
protects lipids, proteins, and DNA from oxidation due to its ability to undergo redox …
protects lipids, proteins, and DNA from oxidation due to its ability to undergo redox …
Crafting a rigorous, clinically relevant large animal model of chronic myocardial ischemia: what have we learned in 20 years?
The past several decades have borne witness to several breakthroughs and paradigm shifts
within the field of cardiovascular medicine, but one component that has remained constant …
within the field of cardiovascular medicine, but one component that has remained constant …
Prevention of contrast induced-acute kidney injury using coenzyme Q10 in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous …
D Ahmadimoghaddam, SS Talebi, A Rahmani… - European Journal of …, 2023 - Springer
Purpose We assessed the potential effect of CoQ10 administration for the prevention of
contrast induced-acute kidney injury (CI-AKI) in patients with ST-segment elevation …
contrast induced-acute kidney injury (CI-AKI) in patients with ST-segment elevation …
Connexin 43 modulates reverse electron transfer in cardiac mitochondria from inducible knock-out Cx43Cre−ER(T)/fl mice by altering the coenzyme Q pool
M Consegal, E Miró-Casas, I Barba… - Basic Research in …, 2024 - Springer
Succinate accumulates during myocardial ischemia and is rapidly oxidized during
reperfusion, leading to reactive oxygen species (ROS) production through reverse electron …
reperfusion, leading to reactive oxygen species (ROS) production through reverse electron …
Mitochondria-targeted combination treatment strategy counteracts myocardial reperfusion injury of aged rats by modulating autophagy and inflammatory response
B Mokhtari, R Badalzadeh - Molecular Biology Reports, 2023 - Springer
Background Aging, as a recognized risk factor for ischemic heart disease, interferes with
protective mechanisms and abolishes the optimal effectiveness of cardioprotective …
protective mechanisms and abolishes the optimal effectiveness of cardioprotective …
[HTML][HTML] Sphingolipid Metabolism Is Associated with Cardiac Dyssynchrony in Patients with Acute Myocardial Infarction
CH Huang, CL Kuo, YS Cheng, CS Huang, CS Liu… - Biomedicines, 2024 - mdpi.com
Aim: Sphingolipids are a class of complex and bioactive lipids that are involved in the
pathological processes of cardiovascular disease. Fabry disease is an X-linked storage …
pathological processes of cardiovascular disease. Fabry disease is an X-linked storage …
[HTML][HTML] Effects of coenzyme Q10 supplementation on oxidative stress biomarkers following reperfusion in STEMI patients undergoing primary percutaneous coronary …
A Yazdi, K Shirmohammadi, E Parvaneh… - … of Cardiovascular and …, 2023 - ncbi.nlm.nih.gov
Methods: Seventy patients with the first attack of STEMI, eligible for PPCI were randomly
assigned to receive either standard treatments plus CoQ10 (400 mg before PPCI and 200 …
assigned to receive either standard treatments plus CoQ10 (400 mg before PPCI and 200 …
Cardioprotective effects of coenzyme Q10 supplementation on patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary …
A Yazdi, K Shirmohammadi, E Parvaneh… - Pharmaceutical …, 2023 - ps.tbzmed.ac.ir
Background: We assessed the potential efficacy of Coenzyme Q10 (CoQ10) in patients with
ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous …
ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous …