Historically, the most successful molecular target for antimalarial drugs has been heme
biomineralization within the malarial parasite digestive vacuole. Heme released from …

The important protozoan parasites including Plasmodium, Leishmania, Toxoplasma,
Trypanosoma and Giardia have been proved as the main reason initiating and developing …

We synthesized a new series of conjugated hydrazones that were found to be active against
malaria parasite in vitro, as well as in vivo in a murine model. These hydrazones …

The isolation of artemisinin from the traditional medicinal herb qīng hāo (Artemisia annua),
its characterization as a peroxide and preparation of the derivatives dihydroartemisinin …

Covering up to 2014 Isocyanoterpenes (ICTs) are marine natural products biosynthesized
through an unusual pathway that adorns terpene scaffolds with nitrogenous functionality …

Despite tremendous advances in the prevention and treatment of infectious diseases, only
few antiparasitic drugs have been developed to date. Protozoan infections such as malaria …

In this study, electrochemical nanosensors were developed from the synthesized metal
oxide (MO) nanoparticles by supporting it on a gold electrode (Au). The activity of the …

This review analyzes the more recent publications concerning the distribution, chemistry,
and bioactivities of naphthoquinones (NQs) in higher plants. These highly reactive …

Over the course of the development of the antimalarial ferroquine, we have developed many
ideas about its specific mechanism of action. Those ideas have enabled us to propose …

The emergence of resistance toward artemisinin combination therapies (ACTs) by the
malaria parasite Plasmodium falciparum has the potential to severely compromise malaria …