Taking into account the vast arrays of fluorinated motifs known, 11 this review will be limited
to the monofluorination of organic compounds, ie, synthetic methods allowing the …

Three-component difunctionalization of alkenes is regarded as one of the most attractive
strategies in synthetic chemistry, because it enables the direct synthesis of useful and …

Abstract α‐Trifluoromethylated ketones have attracted significant attention as valuable
building blocks in organic synthesis. Such compounds are generally accessed through …

Fluoroalkylation reaction, featuring the transfer of a fluoroalkyl group to a substrate, is a
straightforward and efficient method for the synthesis of organofluorine compounds. In …

A new olefination protocol for transition-metal-free cross-coupling of two carbene fragments
arising from two different sources, namely, a nonfluorinated carbene fragment resulting from …

Fluoroalkenes represent a class of privileged structural motifs, which found widespread use
in medicinal chemistry. However, the synthetic access to fluoroalkenes was much …

Transition-metal-catalyzed difunctionalization of olefins constitutes a fertile synthetic platform
for rapid access to complex molecules from bulk chemicals. However, substrates featuring …

The nickel-catalyzed defluorinative coupling of 2-trifluoromethyl-1-alkenes and alkynes with
the aid of Et3SiH provides 1, 1-difluoro-1, 4-dienes under mild reaction conditions. This …

Summary gem-Difluoroalkenes have steric and electronic profiles similar to those of
ketones, aldehydes, and esters, and consequently have been used widely as carbonyl …

A copper catalytic system was established for the stereoselective hydrodefluorination of gem‐
difluoroalkenes through C− F activation to synthesize various Z fluoroalkenes. H2O is used …