Obesity is a metabolic disorder of increasing prevalence worldwide and a risk factor for the
development of insulin resistance (IR), metabolic syndrome and type 2 diabetes. Obesity is …

Obesity is strongly associated with high blood pressure, dyslipidemia, and type 2 diabetes.
These conditions synergistically increase the risk of cardiovascular events. A number of …

Monosodium glutamate (MSG) is one of the most widely spread food additives that might
cause male infertility. However, Nigella sativa L. seeds (NSS) could provide a solution. This …

Background Metabolic syndrome is characterized by insulin resistance, which is closely
related to GLUT4 content in insulin-sensitive tissues. Thus, we evaluated the GLUT4 …

The endothelium plays a vital role in maintaining circulatory homeostasis by the release of
relaxing and contracting factors. Any change in this balance may result in a process known …

Obesity dramatically increases the risk of development of cardiovascular and metabolic
diseases. Endothelial dysfunction induced by obesity is an important risk factor that impairs …

Aims/hypothesis The discovery of osteocalcin, a protein synthetized by osteoblasts, as a
hormone that has positive effects on insulin resistance, contributed to support the concept of …

Introduction Metabolic syndrome induces endothelial dysfunction, a surrogate marker of
cardiovascular disease. In parallel, metabolic syndrome is frequently associated with non …

The endothelium is an established modulator of vascular tone; however, the recent
discovery of the anti‐contractile nature of perivascular adipose tissue (PVAT) suggests that …

Aims Iron overload in animal models and humans increases oxidative stress and induces
cardiomyopathy. It has been suggested that the vasculature is also damaged, but the …