Organogels in drug delivery: a special emphasis on pluronic lecithin organogels

H Alsaab, SP Bonam, D Bahl… - … of Pharmacy & …, 2016 - journals.library.ualberta.ca
Organogels have emerged as an alternative carrier for small and macromolecules via
transdermal, oral, rectal and ophthalmic routes. Pluronic lecithin organogels (PLO gels) are …

[HTML][HTML] Effect of application amounts on in vitro dermal absorption test using caffeine and testosterone

JE Im, HY Kim, JD Lee, JJ Park, KS Kang, KB Kim - Pharmaceutics, 2021 - mdpi.com
Dermal absorption of chemicals is a key factor in risk assessment. This study investigated
the effects of different amounts of application on dermal absorption and suggested an …

[HTML][HTML] Evaluation of Two Novel Hydantoin Derivatives Using Reconstructed Human Skin Model EpiskinTM: Perspectives for Application as Potential Sunscreen …

K Słoczyńska, J Popiół, A Gunia-Krzyżak… - Molecules, 2022 - mdpi.com
This study aimed to assess two novel 5-arylideneimidazolidine-2, 4-dione (hydantoin)
derivatives (JH3 and JH10) demonstrating photoprotective activity using the reconstructed …

Evaluation of Pentravan®, Pentravan® Plus, Phytobase®, Lipovan® and Pluronic Lecithin Organogel for the transdermal administration of antiemetic drugs to treat …

F Bourdon, M Lecoeur, L Leconte, V Ultré… - International journal of …, 2016 - Elsevier
The objective of this study was to evaluate five commercial ready-to-use transdermal
vehicles (Phytobase®, Lipovan®, Pentravan®, Pentravan® Plus and Pluronic Lecithin …

Comparison of the Antifungal Efficacy of Terbinafine Hydrochloride and Ciclopirox Olamine Containing Formulations against the Dermatophyte Trichophyton rubrum …

A Täuber, CC Müller-Goymann - Molecular pharmaceutics, 2014 - ACS Publications
Onychomycosis is a fungal infection mostly induced by dermatophytes such as Trichophyton
rubrum. Due to slow nail growth, the treatment takes 3–9 months depending on the nail size …

Discovery formulations: approaches and practices in early preclinical development

SN Bhattachar, DM Bender, SA Sweetana… - … molecules with optimal …, 2015 - Springer
Reduced portfolio attrition and faster development of high quality drugs that address unmet
medical needs is an established imperative within the pharmaceutical industry. Given the …

Ex-Vivo percutaneous absorption of enrofloxacin: Comparison of LMOG organogel vs. pentravan cream

P Kirilov, A Ducrotté-Tassel, JP Salvi, S Perrot… - International Journal of …, 2016 - Elsevier
The objective of this study was to investigate the percutaneous absorption of enrofloxacin
from two base formulations, Pentravan® cream and LMOG organogel. Ex-vivo experiments …

[HTML][HTML] Compatibility of Different Formulations in Pentravan® and Pentravan® Plus for Transdermal Drug Delivery

H Polonini, S Taylor, C Zander - Scientia Pharmaceutica, 2021 - mdpi.com
The potential therapeutic benefit of transdermal delivery systems for some active
pharmaceutical ingredients (APIs) has been well-established for decades within the …

[HTML][HTML] Transdermal formulations containing human sexual steroids: Development and validation of methods and in vitro drug release

HC Polonini, PP Soldati, MAL Oliveira, MAF Brandão… - Química …, 2014 - SciELO Brasil
In vitro release of bioidentical hormones in four different liposomal transdermal emulsions
(containing testosterone, progesterone, estradiol, or estradiol and estriol) was assessed. For …

Transdermal Oxandrolone: ex vivo percutaneous absorption study

H Polonini, A de Oliveira Ferreira… - Current Drug …, 2017 - ingentaconnect.com
Background: Oxandrolone is a potent synthetic testosterone analogue that possesses strong
anabolic property and weak androgenic activity. Apart of their clinical implicances, oral …