BACKGROUND: Nature has been a source of medicinal products for millennia, with many
useful drugs developed from plant sources. Following discovery of the penicillins, drug …

The cytochrome P450 (CYP) superfamily is the largest enzymatic protein family in plants,
and it also widely exists in mammals, fungi, bacteria, insects and so on. Members of this …

Advances in omics technologies now permit the generation of highly contiguous genome
assemblies, detection of transcripts and metabolites at the level of single cells and high …

Podophyllotoxin is the natural product precursor of the chemotherapeutic etoposide, yet only
part of its biosynthetic pathway is known. We used transcriptome mining in Podophyllum …

Plants produce thousands of secondary metabolites (aka specialized metabolites) of diverse
chemical nature. These compounds play important roles in protecting plants under adverse …

The iridoids comprise a large family of distinctive bicyclic monoterpenes that possess a wide
range of pharmacological activities, including anticancer, anti-inflammatory, antifungal and …

Covering: 2000 to 2014 Plant metabolomics has matured and modern plant metabolomics
has accelerated gene discoveries and the elucidation of a variety of plant natural product …

The medicinal plant Madagascar periwinkle, C atharanthus roseus (L.) G. Don, produces
hundreds of biologically active monoterpene‐derived indole alkaloid (MIA) metabolites and …

Plants represent a huge reservoir of natural products. A broad series of these compounds
now find application for human health. In this respect, the monoterpene indole alkaloids …

Terpenoids are pervasive in nature and display an immense structural diversity. As the
largest category of plant secondary metabolites, terpenoids have important socioeconomic …