Gut OncoMicrobiome Signatures (GOMS) as next-generation biomarkers for cancer immunotherapy

AM Thomas, M Fidelle, B Routy, G Kroemer… - Nature reviews Clinical …, 2023 - nature.com
Oncogenesis is associated with intestinal dysbiosis, and stool shotgun metagenomic
sequencing in individuals with this condition might constitute a non-invasive approach for …

[HTML][HTML] Potential effects of the most prescribed drugs on the microbiota-gut-brain-axis: A review

K Garg, MH Mohajeri - Brain Research Bulletin, 2024 - Elsevier
The link between drug-induced dysbiosis and its influence on brain diseases through gut-
residing bacteria and their metabolites, named the microbiota-gut-brain axis (MGBA) …

[HTML][HTML] Regular use of proton pump inhibitor and the risk of inflammatory bowel disease: pooled analysis of 3 prospective cohorts

B Xia, M Yang, LH Nguyen, Q He, J Zhen, Y Yu, M Di… - Gastroenterology, 2021 - Elsevier
Background & Aims Proton pump inhibitors (PPIs) have a major impact on gut microbiome
and immune function, which in turn, may increase the risk of inflammatory bowel disease …

Interplay between gut microbiota, bone health and vascular calcification in chronic kidney disease

FG Rodrigues, MS Ormanji, IP Heilberg… - European Journal of …, 2021 - Wiley Online Library
Deregulations in gut microbiota may play a role in vascular and bone disease in chronic
kidney disease (CKD). As glomerular filtration rate declines, the colon becomes more …

Impact of the use of proton pump inhibitors on pembrolizumab effectiveness for advanced urothelial carcinoma

I Tomisaki, M Harada, A Minato, Y Nagata… - Anticancer …, 2022 - ar.iiarjournals.org
Background/Aim: This study aimed to clarify the impact of proton pump inhibitors (PPIs) on
oncological outcomes in patients who received pembrolizumab for advanced urothelial …

Meta-analysis of the effects of proton pump inhibitors on the human gut microbiota

J Zhang, C Zhang, Q Zhang, L Yu, W Chen, Y Xue… - BMC microbiology, 2023 - Springer
Mounting evidence has linked changes in human gut microbiota to proton pump inhibitor
(PPI) use. Accordingly, multiple studies have analyzed the gut microbiomes of PPI users, but …

Gastric acid suppressants and cognitive decline in people with or without cognitive impairment

CY Wu, LY Xiong, M Ouk, JS Rabin… - … Research & Clinical …, 2022 - Wiley Online Library
Introduction Studies suggest associations between proton pump inhibitors (PPIs) and
dementia risk; however, many neither considered histamine‐2 receptor antagonists (H2RAs) …

Differential impact of proton pump inhibitor on survival outcomes of patients with advanced urothelial carcinoma treated with chemotherapy versus pembrolizumab

I Tomisaki, M Harada, S Sakano… - … Journal of Urology, 2023 - Wiley Online Library
Objectives We clarified the effect of concomitant proton pump inhibitor use on oncological
outcomes in patients with advanced urothelial carcinoma treated either with chemotherapy …

Inflammatory Bowel Disease-Associated Arthritis Is Associated with Concomitant Autoimmune and Inflammatory Disorders

M Alizadeh, U Wong, BC Siaton, SA Patil… - Digestive Diseases and …, 2024 - Springer
Abstract Background Extraintestinal Manifestations (EIMs) are a common and potentially
debilitating complication of Inflammatory Bowel Diseases (IBD), sometimes requiring …

Acid‐suppressive medication and incidence of chronic childhood immune‐mediated diseases: A scoping review

J Madej, T Atanassova, S McGuire… - Pediatric Allergy and …, 2023 - Wiley Online Library
Background Use of acid‐suppressive medications (ASMs), for example, proton pump
inhibitors (PPIs) and histamine‐2 receptor antagonists (H2RAs), has been rising along with …