Stem cell-based drug delivery strategy for skin regeneration and wound healing: potential clinical applications

W Zhang, X Huang - Inflammation and Regeneration, 2023 - Springer
Stem cell-based therapy is widely accepted to be a promising strategy in tissue regenerative
medicine. Nevertheless, there are several obstacles to applying stem cells in skin …

Regenerative potential of mesenchymal stromal cells in wound healing: unveiling the influence of normoxic and hypoxic environments

M Mahjoor, A Fakouri, S Farokhi, H Nazari… - Frontiers in Cell and …, 2023 - frontiersin.org
The innate and adaptive immune systems rely on the skin for various purposes, serving as
the primary defense against harmful environmental elements. However, skin lesions may …

Application of hypoxia-mesenchymal stem cells in treatment of anaerobic bacterial wound infection: wound healing and infection recovery

E Andalib, M Kashfi, G Mahmoudvand… - Frontiers in …, 2023 - frontiersin.org
Mesenchymal stromal cells, commonly referred to as MSCs, are a type of multipotent stem
cells that are typically extracted from adipose tissue and bone marrow. In the field of tissue …

[HTML][HTML] Novel therapeutical approaches based on neurobiological and genetic strategies for diabetic polyneuropathy–A review

EK Sher, AD Krivić, A Karahmet, M Beca-Zeco… - Diabetes & Metabolic …, 2023 - Elsevier
Background Neuropathy is among the most often reported consequences of diabetes and
the biggest cause of morbidity and mortality in people suffering from this life-long disease …

New insights in application of mesenchymal stem cells therapy in tumor microenvironment: Pros and cons

H Afkhami, G Mahmoudvand, A Fakouri… - Frontiers in Cell and …, 2023 - frontiersin.org
Multipotent mesenchymal stem cells (MSCs) are widely accepted as a useful tool for cell-
based therapy of various diseases including malignancies. The therapeutic effects of MSCs …

Comparative study on the efficacy of PRP gel and UC‐MSCs gel as adjuvant therapies in the treatment of DFU wounds

Y Jin, MY Meng, YF Zhang, L Mo, H Gao… - Skin Research and …, 2024 - Wiley Online Library
Background Diabetic foot ulcer (DFU) is a common and serious complication of diabetes,
and its treatment is challenging. Platelet‐rich plasma (PRP) gel and umbilical cord …

Identification of potential immunologic resilience in the healing process of diabetic foot ulcers

Y Cheng, L Ren, A Niyazi, L Sheng… - International Wound …, 2024 - Wiley Online Library
Diabetic foot ulcers (DFUs) are one of the most common and challenging complications of
diabetes, yet our understanding of their pathogenesis remains limited. We collected gene …

[HTML][HTML] CRISPR-Microfluidics Nexus: Advancing Biomedical Applications for Understanding and Detection

ZS Razavi, M Soltani, H Pazoki-Toroudi… - Sensors and Actuators A …, 2024 - Elsevier
The integration of CRISPR technology with microfluidic-based biosensors has greatly
expanded its applications in medicine and molecular biology. This combination offers …

Mesenchymal stem/stromal cell-derived small extracellular vesicles (MSC-sEVs): a promising treatment modality for diabetic foot ulcer

D Kouroupis, LD Kaplan, C Ricordi, TM Best - Bioengineering, 2023 - mdpi.com
Diabetic foot ulcer (DFU) is associated with neuropathy and/or peripheral artery disease of
the lower limb in diabetic patients, affecting quality of life and leading to repeated …

Regulation of the Nrf2/HO-1 axis by mesenchymal stem cells-derived extracellular vesicles: implications for disease treatment

H Su, Z Wang, L Zhou, D Liu, N Zhang - Frontiers in Cell and …, 2024 - frontiersin.org
This comprehensive review inspects the therapeutic potential of mesenchymal stem cell-
derived extracellular vesicles (MSC-EVs) across multiple organ systems. Examining their …