Regulatory transposable elements in the encyclopedia of DNA elements

AY Du, JD Chobirko, X Zhuo, C Feschotte… - Nature …, 2024 - nature.com
Abstract Transposable elements (TEs) comprise~ 50% of our genome, but knowledge of
how TEs affect genome evolution remains incomplete. Leveraging ENCODE4 data, we …

The role of transposable elements in human evolution and methods for their functional analysis: current status and future perspectives

K Fukuda - Genes & Genetic Systems, 2023 - jstage.jst.go.jp
Transposable elements (TEs) are mobile DNA sequences that can insert themselves into
various locations within the genome, causing mutations that may provide advantages or …

[PDF][PDF] Translation of Genome-Wide Association Studies: From Genomic Signals to Biological Insights

SF Grant, WS Bruner - Frontiers in Genetics, 2024 - frontiersin.org
The pathogenesis of common, complex human traits and diseases emerge as a
consequence of the interplay between environmental and genetic factors. To uncover the …

Multi-species analysis of inflammatory response elements reveals ancient and lineage-specific contributions of transposable elements to NF-κB binding

L Wang, A Alizada, K Rathnakumar, N Khyzha, T Taylor… - bioRxiv, 2022 - biorxiv.org
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is an essential and
evolutionarily conserved transcription factor complex primarily involved in innate immunity …

Cryptic endogenous retrovirus subfamilies in the primate lineage

X Chen, Z Zhang, Y Yan, C Goubert, G Bourque… - bioRxiv, 2023 - biorxiv.org
Many endogenous retroviruses (ERVs) in the human genome are primate-specific and have
contributed novel cis-regulatory elements and transcripts. However, current approaches for …

[PDF][PDF] The Evolution of Transposable Elements as Cis-Regulatory Elements in Mammals

AY Du - Evolution, 2023 - scholar.archive.org
ABSTRACT OF THE DISSERTATION The Evolution of Transposable Elements as Cis-
Regulatory Elements in Mammals for Arts & Sciences Graduate Students by Alan Du Doctor …

Why Biological Evolution Should Inspire Worship

G Finlay - Scientia et Fides, 2024 - apcz.umk.pl
The theory of biological evolution has often provoked disagreement, which has frequently
been divisive and counterproductive. At other times this scientific paradigm has been …

The Evolution of Transposable Elements as Cis-Regulatory Elements in Mammals for Arts & Sciences Graduate Students

A Du - 2023 - search.proquest.com
Transposable elements (TEs) are mobile genetic elements that make up a large proportion
of mammalian genomes. Although TEs are highly prevalent genomic sequences, they have …

The Evolution of NF-κB Mediated Transcriptional Regulation in Mammalian Endothelial Cells

L Wang - 2023 - search.proquest.com
NF-κB is an essential and evolutionarily conserved transcription factor complex primarily
involved in innate immunity and inflammation. In the thesis, I explore how the NF-κB-centric …