Macrophages are critical mediators of the innate immune response against foreign
pathogens, including bacteria, physical stress, and injury. Therefore, these cells play a key …

Subarachnoid hemorrhage (SAH) can lead to devastating neurological outcomes, and there
are few pharmacologic treatments available for treating this condition. Both animal and …

Cordyceps militaris, a traditional medicinal mushroom, produces the bioactive compound
cordycepin (3'-deoxyadenosine). Although cordycepin has been shown to have …

Abstract Pseudoginsenoside-F11 (PF11), an ocotillol-type ginsenoside, has been shown to
possess significant neuroprotective activity. Since microglia-mediated inflammation is critical …

Over-activation of microglia disrupts the physiological homeostasis of the brain, and induces
inflammatory response and other processes which are implicated in neurodegenerative …

Amikacin (AK) has the largest spectrum of aminoglycosides. However, its use is constrained
because of nephrotoxicity and ototoxicity. Ellagic acid (EA) is a polyphenol present in plants …

Aims Hypercholesterolemia is an important risk factor for development of cardiovascular
disturbances, such as atherosclerosis, and its treatment remains challenging in modern …

Inhibition of microglial activation is effective in treating various neurological disorders.
Activation of microglial cannabinoid CB2 receptor induces anti-inflammatory effects, and the …

Objectives: We sought to investigate the timing of restenosis and the restenosis factors
following nitinol stenting in the superficial femoral artery (SFA). Background: Restenosis …

Glaucoma is a leading cause of irreversible blindness. Injury of retinal ganglion cells (RGCs)
accounts for visual impairment of glaucoma. Here, we report rapamycin protects RGCs from …