Cryptochromes (CRYs) are photoreceptors that mediate light regulation of the circadian
clock in plants and animals. Here we show that CRYs mediate blue-light regulation of N6 …

Circadian clocks and metabolism are inextricably intertwined, where central and hepatic
circadian clocks coordinate metabolic events in response to light-dark and sleep-wake …

Circadian (~ 24 hour) clocks have a fundamental role in regulating daily physiology. The
transcription factor BMAL1 is a principal driver of a molecular clock in mammals. Bmal1 …

Genome biology approaches have made enormous contributions to our understanding of
biological rhythms, particularly in identifying outputs of the clock, including RNAs, proteins …

Data integration, data sharing, and standardized analyses are important enablers for data‐
driven medical research. Circadian medicine is an emerging field with a particularly high …

Disrupted sleep-wake and molecular circadian rhythms are a feature of aging associated
with metabolic disease and reduced levels of NAD+, yet whether changes in nucleotide …

INTRODUCTION The circadian clock is a molecular oscillator that coordinates behavior and
physiology in anticipation of the daily light cycle. Desynchrony of circadian cycles, through …

Gut microbial diurnal oscillations are important diet-dependent drivers of host circadian
rhythms and metabolism ensuring optimal energy balance. However, the interplay between …

Simple Summary Personalized cancer treatments show decreased side-effects and
improved treatment success. One aspect of individualized treatment is the timing of medicine …

Circadian clocks regulate membrane excitability in master pacemaker neurons to control
daily rhythms of sleep and wake. Here, we find that two distinctly timed electrical drives …