Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings
Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that
alternate between mania and hypomania or between depression and mixed states, often …
alternate between mania and hypomania or between depression and mixed states, often …
Unravelling the genetic basis of schizophrenia and bipolar disorder with GWAS: A systematic review
Objectives To systematically review findings of GWAS in schizophrenia (SZ) and in bipolar
disorder (BD); and to interpret findings, with a focus on identifying independent replications …
disorder (BD); and to interpret findings, with a focus on identifying independent replications …
Epigenetics applied to psychiatry: clinical opportunities and future challenges
L Kular, S Kular - Psychiatry and clinical neurosciences, 2018 - Wiley Online Library
Psychiatric disorders are clinically heterogeneous and debilitating chronic diseases
resulting from a complex interplay between gene variants and environmental factors …
resulting from a complex interplay between gene variants and environmental factors …
Biomarkers for bipolar disorder: current status and challenges ahead
Introduction: Bipolar disorder (BD) is a chronic psychiatric disorder marked by clinical and
pathophysiological heterogeneity. There is a high expectation that personalized approaches …
pathophysiological heterogeneity. There is a high expectation that personalized approaches …
Differential methylation of enhancer at IGF2 is associated with abnormal dopamine synthesis in major psychosis
Impaired neuronal processes, including dopamine imbalance, are central to the
pathogenesis of major psychosis, but the molecular origins are unclear. Here we perform a …
pathogenesis of major psychosis, but the molecular origins are unclear. Here we perform a …
DNA methylation signature as a biomarker of major neuropsychiatric disorders
Z Shirvani-Farsani, Z Maloum… - Journal of Psychiatric …, 2021 - Elsevier
DNA methylation is a broadly-investigated epigenetic modification that has been considered
as a heritable and reversible change. Previous findings have indicated that DNA methylation …
as a heritable and reversible change. Previous findings have indicated that DNA methylation …
Epigenetics in bipolar disorder: a critical review of the literature
A Legrand, A Iftimovici, A Khayachi… - Psychiatric …, 2021 - journals.lww.com
Methods We searched PubMed, and Embase databases and classified the articles
depending on the epigenetic mechanisms (DNA methylation, histone modifications and non …
depending on the epigenetic mechanisms (DNA methylation, histone modifications and non …
The miRNome of bipolar disorder
Background Epigenetic mechanisms have been suggested to play a key role in the
pathophysiology of bipolar disorder (BD), among which microRNAs (miRNAs) may be of …
pathophysiology of bipolar disorder (BD), among which microRNAs (miRNAs) may be of …
DNA methylation in cancer: epigenetic view of dietary and lifestyle factors
Background: Alterations in DNA methylation play an important role in cancer development
and progression. Dietary nutrients and lifestyle behaviors can influence DNA methylation …
and progression. Dietary nutrients and lifestyle behaviors can influence DNA methylation …
Cohort profile: the Heinz C. Prechter longitudinal study of bipolar disorder
Cohort Profile: The Heinz C. Prechter Longitudinal Study of Bipolar Disorder | International
Journal of Epidemiology | Oxford Academic Skip to Main Content Advertisement intended for …
Journal of Epidemiology | Oxford Academic Skip to Main Content Advertisement intended for …