Importance Sickle cell disease (SCD) is a monogenic disorder, yet clinical outcomes are
influenced by additional genetic factors. Despite decades of research, the genetics of SCD …

The imbalance of oxidation and antioxidant systems in the biological system can lead to
oxidative stress, which is closely related to the pathogenesis of many diseases. Substances …

Sickle cell disease (SCD) is the most common genetic blood disorder in the world and
affects millions of people. With aging, patients encounter an increasing number of …

Latin Americans are an underappreciated population affected by sickle cell disease (SCD).
Sickle trait and SCD exist throughout Latin America and US Latino communities. We …

Background Sickle cell disease (SCD) is a class of hemoglobinopathy resulting from a
single mutation in the ß-globin chain inducing the substitution of valine for glutamic acid at …

Sickle cell disease (SCD) is an inherited hemolytic anemia whose pathophysiology is driven
by polymerization of the hemoglobin S (Hb S), leading to hemolysis and vaso-occlusive …

Developing anticancer sensing platforms has a significant impact on individual cancer
treatment. Monitoring of anticancer drugs in bodily fluid allows doctors to prescript the …

Background Oxidative stress plays a pivotal role in the pathophysiology of sickle cell
disease (SCD) and its associated disease complications. Superoxide Dismutases (SODs) …

This study proposes an efficient antidiabetic strategy by identifying potential mechanisms of
antioxidant metabolism and α‐amylase inhibition in Syzygium cumini L. fruits. Six …

Sickle cell disease (SCD) is an inherited hemoglobin disorder marked by red blood cell
sickling, resulting in severe anemia, painful episodes, extensive organ damage, and …