Methotrexate (MTX) is the first line drug for the treatment of a number of rheumatic and non-
rheumatic disorders. It is currently used as an anchor disease, modifying anti-rheumatic drug …

Reactivation of hepatitis B refers to the abrupt increase in hepatitis B virus (HBV) replication
in a patient with inactive or resolved hepatitis B. Reactivation can occur spontaneously, but …

Background: Drug-induced liver injury (DILI) is an uncommon adverse drug reaction of
increasing importance to the medical community, pharmaceutical industry, regulatory …

Jo Ledingham1, Nicola Gullick2, Katherine Irving2, Rachel Gorodkin3, Melissa Aris3, Jean
Burke4, Patrick Gordon2, Dimitrios Christidis5, Sarah Galloway6, Eranga Hayes7, Andrew …

Background Acute chloroquine and hydroxychloroquine toxicity is characterized by a
combination of direct cardiovascular effects and electrolyte derangements with resultant …

Objective To investigate the kinetics of hepatitis B virus (HBV) viral loads and HBV
reactivation in rheumatoid arthritis (RA) patients undergoing therapy with tumour necrosis …

Hydroxychloroquine (HCQ) has been used for the treatment of novel coronavirus disease
(COVID-19) cases. However, evidence of efficacy remains limited, and adverse events can …

Introduction: Despite the therapeutic effectiveness of biologics targeting immune cells or
cytokines in patients with inflammatory arthritis, which reflects their pathogenic roles, an …

Featuring more than 4100 references, Drug-Induced Liver Disease is an invaluable
reference for gastroenterologists, hepatologists, family physicians, internists, pathologists …

Infections are one of the leading causes of morbidity and mortality in patients with systemic
lupus erythematosus (SLE). Therapeutic, disease-related and genetic factors all contribute …