High-voltage electrical pulses in oncology: irreversible electroporation, electrochemotherapy, gene electrotransfer, electrofusion, and electroimmunotherapy

B Geboers, HJ Scheffer, PM Graybill, AH Ruarus… - Radiology, 2020 - pubs.rsna.org
This review summarizes the use of high-voltage electrical pulses (HVEPs) in clinical
oncology to treat solid tumors with irreversible electroporation (IRE) and …

Irreversible electroporation: background, theory, and review of recent developments in clinical oncology

KN Aycock, RV Davalos - Bioelectricity, 2019 - liebertpub.com
Irreversible electroporation (IRE) has established a clinical niche as an alternative to thermal
ablation for the eradication of unresectable tumors, particularly those near critical vascular …

Irreversible electroporation and electrochemotherapy in oncology: State of the art

JP Tasu, D Tougeron, MP Rols - Diagnostic and Interventional Imaging, 2022 - Elsevier
Thermal tumor ablation techniques including radiofrequency, microwave, LASER, high-
intensity focused ultrasound and cryoablation are routinely used to treated liver, kidney …

Electrotherapies for glioblastoma

EPW Jenkins, A Finch, M Gerigk, IF Triantis… - Advanced …, 2021 - Wiley Online Library
Abstract Non‐thermal, intermediate frequency (100–500 kHz) electrotherapies present a
unique therapeutic strategy to treat malignant neoplasms. Here, pulsed electric fields (PEFs) …

Extended focal ablation of localized prostate cancer with high-frequency irreversible electroporation: a nonrandomized controlled trial

H Wang, W Xue, W Yan, L Yin, B Dong, B He… - JAMA …, 2022 - jamanetwork.com
Importance Focal therapy of prostate cancer must balance the oncologic outcome and
functional outcome. High-frequency irreversible electroporation (H-FIRE) can destroy cancer …

Cancellation effect is present in high-frequency reversible and irreversible electroporation

T Polajžer, J Dermol–Černe, M Reberšek… - …, 2020 - Elsevier
It was recently suggested that applying high-frequency short biphasic pulses (HF-IRE)
reduces pain and muscle contractions in electrochemotherapy and irreversible ablation …

A theoretical argument for extended interpulse delays in therapeutic high-frequency irreversible electroporation treatments

KN Aycock, Y Zhao, MF Lorenzo… - IEEE Transactions on …, 2021 - ieeexplore.ieee.org
High-frequency irreversible electroporation (H-FIRE) is a tissue ablation modality employing
bursts of electrical pulses in a positive phase–interphase delay (d 1)–negative phase …

Pulsed electric fields in oncology: A snapshot of current clinical practices and research directions from the 4th world congress of electroporation

LG Campana, A Daud, F Lancellotti, JP Arroyo… - Cancers, 2023 - mdpi.com
Simple Summary Locoregional therapies play an ever-increasing role in contemporary
oncology. This review provides an up-to-date, informed analysis of locoregional therapies …

[HTML][HTML] Reduction of muscle contraction and pain in electroporation-based treatments: An overview

R Fusco, E Di Bernardo, V D'Alessio… - World Journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND In the first studies of electrochemotherapy (ECT), small cutaneous
metastases were treated and only mild or moderate pain was observed; therefore, pain was …

[PDF][PDF] The good and the bad of cell membrane electroporation.

K Balantič, D Miklavčič, I Križaj, P Kramar - Acta Chimica Slovenica, 2021 - lbk.fe.uni-lj.si
Electroporation is used to increase the permeability of the cell membrane through high-
voltage electric pulses. Nowadays, it is widely used in different areas, such as medicine …