Genomics insights of SARS-CoV-2 (COVID-19) into target-based drug discovery
P Chellapandi, S Saranya - Medicinal Chemistry Research, 2020 - Springer
Abstract Coronavirus disease (COVID-19) pandemic is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is a global health emergency and no …
syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is a global health emergency and no …
Molecular docking as a potential approach in repurposing drugs against COVID-19: A systematic review and novel pharmacophore models
M Fadlalla, M Ahmed, M Ali, AA Elshiekh… - Current Pharmacology …, 2022 - Springer
Abstract Purpose of Review This article provides a review of the recent literature related to
the FDA-approved drugs that had been repurposed as potential drug candidates against …
the FDA-approved drugs that had been repurposed as potential drug candidates against …
Quick and efficient quantitative predictions of androgen receptor binding affinity for screening endocrine disruptor chemicals using 2D-QSAR and chemical read …
Abstract Endocrine Disruptor Chemicals are synthetic or natural molecules in the
environment that promote adverse modifications of endogenous hormone regulation in …
environment that promote adverse modifications of endogenous hormone regulation in …
Identification of potential inhibitors of SARS-CoV-2 main protease and spike receptor from 10 important spices through structure-based virtual screening and …
The outbreak of novel coronavirus disease (COVID-19) caused by SARS-CoV-2 poses a
serious threat to human health and world economic activity. There is no specific drug for the …
serious threat to human health and world economic activity. There is no specific drug for the …
Targeting SARS-CoV-2 main protease: a computational drug repurposing study
Background and Aims Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)
induced Novel Coronavirus Disease (COVID-19) has currently become pandemic …
induced Novel Coronavirus Disease (COVID-19) has currently become pandemic …
In silico and in vitro studies of GENT-EDTA encapsulated niosomes: A novel approach to enhance the antibacterial activity and biofilm inhibition in drug-resistant …
I Akbarzadeh, N Rezaei, S Bazzazan, MN Mezajin… - Biomaterials …, 2023 - Elsevier
Klebsiella pneumoniae (Kp) is a common pathogen inducing catheter-related biofilm
infections. Developing effective therapy to overcome antimicrobial resistance (AMR) in Kp is …
infections. Developing effective therapy to overcome antimicrobial resistance (AMR) in Kp is …
In silico analysis and identification of antiviral coumarin derivatives against 3-chymotrypsin-like main protease of the novel coronavirus SARS-CoV-2
Abstract Coronavirus disease 2019 (COVID-19) is a pandemic viral disease caused by
SARS-CoV-2 that generated serious damages for both the human population and the global …
SARS-CoV-2 that generated serious damages for both the human population and the global …
Designing short peptides to block the interaction of SARS-CoV-2 and human ACE2 for COVID-19 therapeutics
To date, the current COVID-19 pandemic caused by SARS-CoV-2 has infected 99.2 million
while killed 2.2 million people throughout the world and is still spreading widely. The …
while killed 2.2 million people throughout the world and is still spreading widely. The …
Importance of glutamine 189 flexibility in SARS-CoV-2 main protease: Lesson learned from in silico virtual screening of ChEMBL database and molecular dynamics
The current global pandemic outbreak of COVID-19, caused by the SARS-CoV-2, strikes an
invincible damage to both daily life and the global economy. WHO guidelines for COVID-19 …
invincible damage to both daily life and the global economy. WHO guidelines for COVID-19 …
Binding and inhibitory effect of ravidasvir on 3CLpro of SARS-CoV‐2: a molecular docking, molecular dynamics and MM/PBSA approach
K Bera - Journal of Biomolecular Structure and Dynamics, 2022 - Taylor & Francis
Drug repurposing requires a limited resource, cost-effective and faster method to combat
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therefore, this in silico …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therefore, this in silico …