CXCL10 chemokine: a critical player in RNA and DNA viral infections
Chemokines constitute a group of small, secreted proteins that regulate leukocyte migration
and contribute to their activation. Chemokines are crucial inflammatory mediators that play a …
and contribute to their activation. Chemokines are crucial inflammatory mediators that play a …
[HTML][HTML] Beyond HIV infection: neglected and varied impacts of CCR5 and CCR5Δ32 on viral diseases
The interactions between chemokine receptors and their ligands may affect susceptibility to
infectious diseases as well as their clinical manifestations. These interactions mediate both …
infectious diseases as well as their clinical manifestations. These interactions mediate both …
Zika virus infection promotes local inflammation, cell adhesion molecule upregulation, and leukocyte recruitment at the blood-brain barrier
The blood-brain barrier (BBB) largely prevents toxins and pathogens from accessing the
brain. Some viruses have the ability to cross this barrier and replicate in the central nervous …
brain. Some viruses have the ability to cross this barrier and replicate in the central nervous …
Association between genetic variants in TREM1, CXCL10, IL4, CXCL8 and TLR7 genes with the occurrence of congenital Zika syndrome and severe microcephaly
CNO Santos, LS Magalhães, ABL Fonseca… - Scientific Reports, 2023 - nature.com
Congenital Zika syndrome (CZS) is a cluster of malformations induced by Zika virus (ZIKV)
infection and the underline mechanisms involved in its occurrence are yet not fully …
infection and the underline mechanisms involved in its occurrence are yet not fully …
Zika virus differentially infects human neural progenitor cells according to their state of differentiation and dysregulates neurogenesis through the Notch pathway
P Ferraris, M Cochet, R Hamel… - Emerging microbes & …, 2019 - Taylor & Francis
Zika virus (ZIKV) is a mosquito-borne Flavivirus that causes Zika disease with particular
neurological complications, including Guillain-Barré Syndrome and congenital …
neurological complications, including Guillain-Barré Syndrome and congenital …
Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytes
The connection between Zika virus (ZIKV) and neurodevelopmental defects is widely
recognized, although the mechanisms underlying the infectivity and pathology in primary …
recognized, although the mechanisms underlying the infectivity and pathology in primary …
The transcriptional and protein profile from human infected neuroprogenitor cells is strongly correlated to Zika virus microcephaly cytokines phenotype evidencing a …
MC Lima, LR Mendonça, AM Rezende… - Frontiers in …, 2019 - frontiersin.org
Zika virus (ZIKV) infection during pregnancy is associated with microcephaly, a congenital
malformation resulting from neuroinflammation and direct effects of virus replication on the …
malformation resulting from neuroinflammation and direct effects of virus replication on the …
Comprehensive immunoprofiling of pediatric zika reveals key role for monocytes in the acute phase and no effect of prior dengue virus infection
Zika virus (ZIKV) is an emerging, mosquito-borne flavivirus responsible for recent epidemics
across the Americas, and it is closely related to dengue virus (DENV). Here, we study …
across the Americas, and it is closely related to dengue virus (DENV). Here, we study …
Th17 Cells in Viral Infections—Friend or Foe?
IA Paiva, J Badolato-Correa, D Familiar-Macedo… - Cells, 2021 - mdpi.com
Th17 cells are recognized as indispensable in inducing protective immunity against bacteria
and fungi, as they promote the integrity of mucosal epithelial barriers. It is believed that Th17 …
and fungi, as they promote the integrity of mucosal epithelial barriers. It is believed that Th17 …
[HTML][HTML] Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues
SS Ponia, SJ Robertson, KL McNally, G Subramanian… - Cell Reports, 2021 - cell.com
Dysregulated inflammation dominated by chemokine expression is a key feature of disease
following infection with the globally important human pathogens Zika virus (ZIKV) and …
following infection with the globally important human pathogens Zika virus (ZIKV) and …